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Closed-Loop Recycling Dual-Mode Counter-Current Chromatography with Specified Sample Loading Durations: Modeling of Preparative and Industrial-Scale Separations [PDF]

open access: yesMolecules, 2021
We previously reported on a new counter-current chromatography (CCC) operating mode called closed-loop recycling dual-mode counter-current chromatography (CLR DM CCC), which incorporates the advantages of closed-loop recycling (CLR) and dual-mode (DM ...
Artak E. Kostanyan, Andrey A. Voshkin
doaj   +2 more sources

Continuous Affinity Purification of Adeno-Associated Virus Using Periodic Counter-Current Chromatography [PDF]

open access: yesPharmaceutics, 2022
Replacing batch unit operations of biopharmaceuticals by continuous manufacturing is a maturing concept, with periodic counter-current chromatography (PCC) favoured to replace batch chromatography.
João P. Mendes   +5 more
doaj   +2 more sources

Counter-current motion in counter-current chromatography [PDF]

open access: yesJournal of Chromatography A, 2014
After the CCC2012 meeting, I have received an e-mail regarding the terminology of "Countercurrent Chromatography". It stated that the term "Countercurrent" is a misnomer, because its stationary phase is motionless in the column and that the method should be renamed as liquid-liquid separations or centrifugal separations.
Ito Y.
openaire   +3 more sources

Vortex counter-current chromatography [PDF]

open access: yesJournal of Chromatography A, 2011
A novel counter-current chromatographic system is developed by mounting a vortex column on a type-I coil planet centrifuge. The column is fabricated from a high-density polyethylene disk (16 cm diameter and 5 cm thick) by making multiple holes of various diameters (3-12.5 mm) each arranged in a circle and connected with narrow transfer ducts.
Yoichiro, Ito   +5 more
openaire   +3 more sources

One-Step Preparative Separation of Flavone and Isoflavone Glycosides from Sophora Japonica Fruit by High-Speed Counter-Current Chromatography Based on COSMO-RS Model [PDF]

open access: yesInternational Journal of Nutrition Sciences, 2021
Background: Sophora japonica L. (Leguminosae), a well-known traditional medicine in Asia, is offcially listed in the Chinese and European Pharmacopoeia.
Zhao Wang, Yang Liu, Chen Fan, Xueli Cao
doaj   +1 more source

Scale-up of Aflatoxin Purification by Centrifugal Partition Chromatography

open access: yesToxins, 2023
Aflatoxins (AFs) are a group of secondary metabolites that cause several diseases in both animals and humans. Since the discovery of this group of toxins, several effects were revealed, such as hepatic changes, carcinoma, failure, and cancer of the liver.
Gábor Endre   +5 more
doaj   +1 more source

High speed counter current chromatography: A support-free LC technique

open access: yesJournal of Pharmacy and Bioallied Sciences, 2009
As separation of components is the major requirement of an analytical chemist, there is always a need for a convenient high throughput technique with minimum sample loss, high efficiency, high resolution, and ease of sample recovery, without ...
Neha Sethi   +5 more
doaj   +3 more sources

Alternative Extraction and Downstream Purification Processes for Anthocyanins

open access: yesMolecules, 2022
Anthocyanins are natural pigments displaying different attractive colors ranging from red, violet, to blue. These pigments present health benefits that increased their use in food, nutraceuticals, and the cosmetic industry.
Ana N. Nunes   +4 more
doaj   +1 more source

Easy Computation of the Various Topologies and Modes of Liquid–Liquid Partition Chromatography by the Theory of Random Walks

open access: yesSeparations, 2021
The article revisits the discrete recurrence method to model the instruments of liquid–liquid partition chromatography as counter-current chromatography (CCC) and centrifugal partition chromatography (CPC).
Frédéric R. Dijoux, Tsvetelina Mandova
doaj   +1 more source

Development and Testing of a 4-Columns Periodic Counter-Current Chromatography System Based on Membrane Adsorbers

open access: yesSeparations, 2019
Continuous chromatography can surmount the disadvantages of batch chromatography like low productivities and extensive usage of consumables. In this work, a 4-column continuous chromatographic system based on the principle of periodic counter-current ...
Chantal Brämer   +3 more
doaj   +1 more source

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