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Closed-Loop Recycling Dual-Mode Counter-Current Chromatography with Specified Sample Loading Durations: Modeling of Preparative and Industrial-Scale Separations [PDF]

open access: yesMolecules, 2021
We previously reported on a new counter-current chromatography (CCC) operating mode called closed-loop recycling dual-mode counter-current chromatography (CLR DM CCC), which incorporates the advantages of closed-loop recycling (CLR) and dual-mode (DM ...
Artak E. Kostanyan, Andrey A. Voshkin
doaj   +4 more sources

Continuous Affinity Purification of Adeno-Associated Virus Using Periodic Counter-Current Chromatography [PDF]

open access: yesPharmaceutics, 2022
Replacing batch unit operations of biopharmaceuticals by continuous manufacturing is a maturing concept, with periodic counter-current chromatography (PCC) favoured to replace batch chromatography.
João P. Mendes   +5 more
doaj   +2 more sources

Counter-current motion in counter-current chromatography. [PDF]

open access: yesJ Chromatogr A, 2014
After the CCC2012 meeting, I have received an e-mail regarding the terminology of "Countercurrent Chromatography". It stated that the term "Countercurrent" is a misnomer, because its stationary phase is motionless in the column and that the method should be renamed as liquid-liquid separations or centrifugal separations.
Ito Y.
europepmc   +4 more sources

High-Speed Counter-Current Chromatography in Separation and Identification of Saponins from Beta vulgaris L. Cultivar Red Sphere [PDF]

open access: yesPolish Journal of Food and Nutrition Sciences, 2020
Saponins, natural plant compounds exhibiting health benefits, were extracted from B. vulgaris L. cultivar (cv.) Red Sphere and separated by high-speed counter-current chromatography (HSCCC) in a new solvent system composed of: TBME-BuOH-ACN-H2O (1:2:1 ...
Aneta Ewa Spórna-Kucab   +1 more
doaj   +2 more sources

Two-phase Motion in Hydrodynamic Counter-current Chromatography. [PDF]

open access: yesCurr Chromatogr, 2020
Background: Motion of the two mutually immiscible liquids in hydrodynamic countercurrent chromatographic systems is speculated based on the observation of their behavior in a closed coiled tube rotating in unit gravity. Materials and Methods: The experiment revealed an up and down pattern of four stages of twophase volume ratio occupied at the head ...
Ito Y.
europepmc   +4 more sources

Preparative Fractionation of Brazilian Red Propolis Extract Using Step-Gradient Counter-Current Chromatography [PDF]

open access: yesMolecules
Propolis is a resinous bee product with a very complex composition, which is dependent upon the plant sources that bees visit. Due to the promising antimicrobial activities of red Brazilian propolis, it is paramount to identify the compounds responsible ...
Begoña Gimenez-Cassina Lopez   +7 more
doaj   +2 more sources

Vortex counter-current chromatography. [PDF]

open access: yesJ Chromatogr A, 2011
A novel counter-current chromatographic system is developed by mounting a vortex column on a type-I coil planet centrifuge. The column is fabricated from a high-density polyethylene disk (16 cm diameter and 5 cm thick) by making multiple holes of various diameters (3-12.5 mm) each arranged in a circle and connected with narrow transfer ducts.
Ito Y   +5 more
europepmc   +4 more sources

A Novel 3D-Printed and Miniaturized Periodic Counter Current Chromatography System for Continuous Purification of Monoclonal Antibodies [PDF]

open access: yesMicromachines
Continuous chromatography has emerged as one of the most attractive methods for protein purification. Establishing such systems involves installing several chromatographic units in series to enable continuous separation processes and reduce the cost of ...
Carlotta Kortmann   +4 more
doaj   +2 more sources

A multilayer coil in type-I counter-current chromatography. [PDF]

open access: yesJ Chromatogr A, 2018
In the present study, a novel model of type-I counter-current chromatography was developed to simplify the separation column manufacture and extend its application ranges. In this system, a multilayer coil was used as the separation column of type-I counter-current chromatography for the first time. The chromatographic performance of this apparatus was
Yang Y   +5 more
europepmc   +4 more sources

Preparative separation of polyphenols from artichoke by polyamide column chromatography and high-speed counter-current chromatography [PDF]

open access: yesQuímica Nova, 2013
An efficient method for the rapid separation and purification of polyphenols from artichoke by polyamide column chromatography in combination with high-speed counter-current chromatography (HSCCC) was successfully built.
Xikai Shu   +7 more
doaj   +3 more sources

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