Results 51 to 60 of about 61,204 (295)

Purification of paeoniflorin from Paeonia lactiflora Pall. by high-speed counter-current chromatography [PDF]

open access: yes, 2004
High-speed counter-current chromatography was successfully used for the first time for the preparative separation and purification of paeoniflorin from the Chinese medicinal plant Paeonia lactiflora Pall.
Jiang, Y, Lu, HT, Chen, F
core   +1 more source

Isolation of Phenolics from by Combined Counter-current Chromatography and Gel-Filtration

open access: yesNatural Product Communications, 2014
Nine phenolic compounds, quercetin, epi -catechin, catechin, 4-hydroxybenzoic acid, kaempferol 3- O -β-glucopyranoside, quercetin 3- O -β-glucopyranoside, quercetin 3- O -6″- trans -coumaroyl-β-glucoside, kaempferol 3- O -β-rutinoside and quercetin 3- O -
Fernanda das Neves Costa   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Enantioseparation using a counter-current bioreactor [PDF]

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The potential of countercurrent chromatography (CCC) as a small footprint bioreactor/separator for manufacture of enantiopure chiral molecules was explored,
Grudzien, Lukasz
core  

Sample injection strategy to increase throughput in counter-current chromatography: Case study of Honokiol purification [PDF]

open access: yes, 2016
Counter-current chromatography (CCC) has been widely used as a preparative separation method to purify natural products from plant extracts and fermentation broths.
Chen, L   +7 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Advanced modelling and visualisation of liquid-liquid separations of complex sample components, with variable phase distribution and mode of operation [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This research is about liquid-liquid chromatography modelling.
De Folter, Jozefus Johannes Martinus
core  

Isolation and Purification of Oridonin from the Whole Plant of Isodon rubescens by High-Speed Counter-Current Chromatography

open access: yesMolecules, 2011
Semi-preparative high-speed counter-current chromatography (HSCCC) was successfully used for isolation and purification of oridonin from Isodon rubescens by using a two-phase-solvent system composed of n-hexane-ethyl acetate-methanol-water (2.8:5:2.8:5 ...
ChunYue Yu   +7 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Control strategy for multi-column continuous periodic counter current chromatography subject to fluctuating inlet stream concentration [PDF]

open access: yes, 2022
Fluctuations of the inlet feed stream concentration are a challenge in controlling continuous multicolumn counter current chromatography systems with standard methods. We propose a new control strategy based on calculated product column breakthrough from
Bi, J.   +3 more
core   +1 more source

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