Results 191 to 200 of about 11,225 (310)
CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells
AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu +6 more
wiley +1 more source
Green revolution breeding favored water conservation, but weakened water use sensitivity to rising vapor pressure deficit in US spring wheat. [PDF]
Koehler T +5 more
europepmc +1 more source
An immunomagnetic‐MXene bifunctional probe integrated with THz metamaterials enables ultrasensitive and specific detection of pancreatic cancer‐derived exosomes. Dual biomarker recognition ensures high specificity, while MXene signal amplification achieves a detection limit of 647 particles mL−1.
Weidong Jin +8 more
wiley +1 more source
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo +15 more
wiley +1 more source
Pharmaceutical profile and prescribing practices in compounding pharmacies in Brazil: a cross-sectional study. [PDF]
Calado GP +3 more
europepmc +1 more source
Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology
Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen +12 more
wiley +1 more source
Transgressive Acts: Michel Foucault's Lessons on Resistance for Nurses. [PDF]
Moreno-Mulet C +4 more
europepmc +1 more source

