Results 201 to 210 of about 11,225 (310)

CRISPR‐Scan: Cas13a Mismatch Tolerance Enabled Ultra‐Multiplexed Detection of Same‐Site Indels in Acute Myeloid Leukemia

Advanced Science, EarlyView.
Accurately detecting diverse same‐locus insertions or deletions (indels) remains challenging. This study reveals the mismatch‐tolerance profile of LwaCas13a and establishes CRISPR‐Scan, which uses a single crRNA to detect multiple same‐locus indels. The one‐pot assay detects nucleophosmin 1 (NPM1) mutant allele frequencies down to 0.01%, agrees with ...
Linlin Bai, Bei Wang, Mingmin Shi, Dianwei Liu, Huimin Ji, Ting Wang, Ziwei Wang, Kaiming Guo, Xinyang Dou, Chunyan Qian, Fang Zhang, Yongming Wang, Hongju Mao, Rui Wang   +13 more
wiley   +1 more source

The Achille's heel of Prof. Friedman's counter-revolution. A reply

PSL Quarterly Review, 2017
A. GAMBINO
doaj   +1 more source

Enamel nanocrystal misorientation increased with meat-eating and agriculture. [PDF]

Nature
Gilbert PUPA, Green DR, Mahoney P, Guatelli-Steinberg D, Scott McGraw W, Lagan E, Manthi FK, Muteti S, Ndiema E, Ramirez Rozzi F, Stifler CA, Schmidt CA, Achinuq BQ, Scholl A, Gilbert B, O'Hara MC.   +15 more
europepmc   +1 more source

Spatiotemporal Computational Meta‐Imager for Broadband Dual‐Layer Optical Convolution

Advanced Science, EarlyView.
A single‐layer polarization‐multiplexed meta‐imager achieves factorized dual‐layer broadband convolution via spatiotemporal kernel decomposition. Fixed Bessel‐vortex bases and time‐sequential liquid‐crystal modulation deliver tunable signed weights and in‐situ fabrication‐error compensation. Experiments verify improved classification performance across
Mengguang Wang, Chenglong Zheng, Huaping Zang, Changwei Zhang, Huai Xia, Chang Wang, Zhenrong Zheng   +6 more
wiley   +1 more source

The scope of the global history of science: an essay on James Poskett's Horizons. [PDF]

Hist Cienc Saude Manguinhos
Serrano-Juarez JD, Becerra-Bressant B, Ornelas-Cruces M, Gutierrez-Gaytan NS, Galvan D, Granados-Riveros L, Villegas-Lopez T, Villela-González MA.   +7 more
europepmc   +1 more source

Efficient In‐Hardware Matrix–Vector Multiplication and Addition Exploiting Bilinearity of Schottky Barrier Transistors Processed on Industrial FDSOI

Advanced Electronic Materials, EarlyView.
ABSTRACT Machine learning and Artificial Intelligence (AI) tasks have stretched traditional hardware to its limits. In‐hardware computation is a novel approach that aims to run complex operations, such as matrix–vector multiplication, directly at the device level for increased efficiency.
Juan P. Martinez, Niladri Bhattacharjee, Yuxuan He, Giulio Galderisi, Brojogopal Sapui, Sara Mannaa, Ian O'Connor, Violetta Sessi, Peter Javorka, Thomas Mikolajick, Jens Trommer   +10 more
wiley   +1 more source

Politics, geopolitics, and the history of science: on James Secord's "Inventing the scientific revolution". [PDF]

Hist Cienc Saude Manguinhos
Barahona A, Becerra-Bressant B, Galván-Escobar D, Granados-Riveros L, Ornelas-Cruces M, Raj K, Serrano-Juárez D, Torrens E, Villegas-López T, Villela-González MA.   +9 more
europepmc   +1 more source

Safety of Sodium‐Ion Batteries: Evaluation and Perspective from Component Materials to Cells, Modules, and Packs

Advanced Energy Materials, EarlyView.
This review provides a bottom‐up evaluation of sodium‐ion battery safety, linking material degradation mechanisms, cell engineering parameters, and module/pack assembly. It emphasizes that understanding intrinsic material stability and establishing coordinated engineering control across hierarchical levels are vital for preventing degradation coupling ...
Won‐Gwang Lim, Seoa Kim, Erik A. Wu, Darren H. S. Tan, Shawn Peng, Xiaolin Li   +5 more
wiley   +1 more source

Developing a Histology-Based Artificial Intelligence Biomarker to Predict Adjuvant Chemotherapy Benefit in Pancreatic Cancer. [PDF]

J Clin Oncol
Beaufils A, De Martino J, Jiang X, Blanchard T, Fraunhoffer N, Mendes D, Pignolet C, Bourega T, Meneghetti AR, Sainath S, Albuquerque M, Colnot N, Tihy M, Turpin A, Ben Abdelghani M, Wei A, Mitry E, Lecomte T, Biagi J, Artru P, Evesque L, Lambert A, Renouf DJ, Mauduit M, Dusetti NJ, Hammel P, Conroy T, Bachet JB, de Mestier L, Rebours V, Cros J, Kather JN, Nicolle R.   +32 more
europepmc   +1 more source

Deciphering Intricacies in Directional CO2 Conversion From Electrolysis to CO2 Batteries

Advanced Energy Materials, EarlyView.
This review will delve into the inherent connections and distinctions of CO2‐directed conversion in ECO2RR and CO2 batteries, in terms of product types, catalyst selection, catalytic mechanisms, and electrochemical performances, while proposing a benchmarking framework for the evaluation of CO2 batteries and innovative CO2 battery configurations for ...
Changfan Xu, Huaping Zhao, Lizhuang Chen, Weidong Shi, Guosheng Shao, Yong Lei   +5 more
wiley   +1 more source