Results 31 to 40 of about 44,546 (236)

A Biocompatible Liquid Pillar[n]arene-Based Drug Reservoir for Topical Drug Delivery

Pharmaceutics, 2022
Advanced external preparations that possess a sustained-release effect and integrate few irritant elements are urgently needed to satisfy the special requirements of topical administration in the clinic.
Yahan Zhang, Mengke Ma, Longming Chen, Xinbei Du, Zhao Meng, Han Zhang, Zhibing Zheng, Junyi Chen, Qingbin Meng   +8 more
doaj   +1 more source

Transferrin receptor targeting segment T7 containing peptide gene delivery vectors for efficient transfection of brain tumor cells

Drug Delivery, 2022
Successful gene therapy for brain tumors are often limited by two important factors, the existence of blood brain barrier (BBB) and inefficient transfection of brain tumor cells.
Ziyao Kang, Chunlan Zeng, Long Tian, Taoran Wang, Sen Yang, Qin Cheng, Jing Zhang, Qingbin Meng, Changhao Zhang, Zhao Meng   +9 more
doaj   +1 more source

Self‐Assembled Monolayers in p–i–n Perovskite Solar Cells: Molecular Design, Interfacial Engineering, and Machine Learning–Accelerated Material Discovery

Advanced Materials, EarlyView.
This review highlights the role of self‐assembled monolayers (SAMs) in perovskite solar cells, covering molecular engineering, multifunctional interface regulation, machine learning (ML) accelerated discovery, advanced device architectures, and pathways toward scalable fabrication and commercialization for high‐efficiency and stable single‐junction and
Asmat Ullah, Ying Luo, Stefaan De Wolf
wiley   +1 more source

Aging erythrocyte membranes as biomimetic nanometer carriers of liver-targeting chromium poisoning treatment

Drug Delivery, 2021
Chromium poisoning has become one of the most common heavy metal poisoning occupational diseases with high morbidity and mortality. However, most antidotes detoxify the whole body and are highly toxic.
Qing Yao, Guobao Yang, Hao Wang, Jingzhou Liu, Jinpeng Zheng, Bai Lv, Meiyan Yang, Yang Yang, Chunsheng Gao, Yongxue Guo   +9 more
doaj   +1 more source

Effect of Surfactants and Polymers on the Dissolution Behavior of Supersaturable Tecovirimat-4-Hydroxybenzoic Acid Cocrystals

Pharmaceutics, 2021
(1) Background: Pharmaceutical cocrystals have attracted remarkable interest and have been successfully used to enhance the absorption of poorly water-soluble drugs.
Yumiao Feng, Yuanyuan Meng, Fangyun Tan, Lin Lv, Zhiping Li, Yuli Wang, Yang Yang, Wei Gong, Meiyan Yang   +8 more
doaj   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Blind Recognition of Forward Error Correction Codes Based on Recurrent Neural Network

Sensors, 2021
Forward error correction coding is the most common way of channel coding and the key point of error correction coding. Therefore, the recognition of which coding type is an important issue in non-cooperative communication.
Fan Mei, Hong Chen, Yingke Lei
doaj   +1 more source

Programmable Klebsiella pneumoniae Phage Tropism Enabled by Scalable Receptor‐Binding Protein Mining and Modular Assembly

Advanced Science, EarlyView.
This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing, Yiyao Song, Xianbiao Bi, Yuqin Song, Dawei Wei, Jiangqing Huang, Yuan Zeng, Gang Zhang, Rong Zhang, Chao Wang, Jie Feng   +10 more
wiley   +1 more source

Two-Dimensional Angle Estimation of Two-Parallel Nested Arrays Based on Sparse Bayesian Estimation

Sensors, 2018
To increase the number of estimable signal sources, two-parallel nested arrays are proposed, which consist of two subarrays with sensors, and can estimate the two-dimensional (2-D) direction of arrival (DOA) of signal sources.
Lu Chen, Daping Bi, Jifei Pan
doaj   +1 more source

Recognizing Non-Collaborative Radio Station Communication Behaviors Using an Ameliorated LeNet

Sensors, 2020
This work improves a LeNet model algorithm based on a signal’s bispectral features to recognize the communication behaviors of a non-collaborative short-wave radio station.
Zilong Wu, Hong Chen, Yingke Lei
doaj   +1 more source