Results 61 to 70 of about 44,546 (236)

Polymer Distribution and Mechanism Conversion in Multiple Media of Phase-Separated Controlled-Release Film-Coating

open access: yesPharmaceutics, 2019
Phase-separated films of water-insoluble ethyl cellulose (EC) and water-soluble hydroxypropyl cellulose (HPC) can be utilized to tailor drug release from coated pellets. In the present study, the effects of HPC levels and the pH, type, ionic strength and
Lu Chen   +9 more
doaj   +1 more source

A “Two‐Pronged” Strategy Boosting the Activity and Stability of Nickel–Iron Catalysts Toward Anion Exchange Membrane Water Electrolysis

open access: yesCarbon Energy, EarlyView.
A “two‐pronged” strategy has been developed to construct a substrate‐strengthened, organophosphorus‐protected nickel‐iron electrode for efficient and robust OER electrocatalysis. Owing to the reinforced catalyst–substrate interaction and minimized active site loss by organophosphorus protection, the integrated electrode serves as an robust and ...
Yansong Zhou   +12 more
wiley   +1 more source

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

open access: yesChemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher   +12 more
wiley   +1 more source

Promoting Sustainability in Healthcare: Unraveling the Mechanism of Diversity's Impact in the Pharmaceutical Sector

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Although research on sustainability in the healthcare sector is growing, limited attention has been paid to how pharmaceutical companies can be motivated to engage more actively in achieving net‐zero healthcare goals. This study argues that the breadth of directors' experiences—across educational, industrial, and organizational domains—can ...
Ruixin Su, Jianguo Du, Si Li
wiley   +1 more source

The Evolution of Environmental, Social, and Governance (ESG) and Risk and Its Implications for Sustainable Finance: A Systematic Literature Review

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Recent literature addressing ESG and risk has increased by 70% since mid‐2022, reflecting a growing interest in sustainable finance. Guided by the PRISMA flow diagram, this paper employs a hybrid systematic review methodology, combining bibliometric analysis with content analysis, to provide a comprehensive overview of the evolution of ESG and
Fahad Asmi, Alain Neher, Alfred Wong
wiley   +1 more source

PPARγ-responsive luciferase reporter system for high-throughput screening of chemical toxins with potential pulmonary fibrosis effects

open access: yesEcotoxicology and Environmental Safety
Background: Pulmonary fibrosis (PF) is a progressive and fatal lung disorder, and emerging evidence suggests that dysregulation of peroxisome proliferator-activated receptor gamma (PPARγ) plays a critical role in its pathogenesis.
Xueyang Lin   +17 more
doaj   +1 more source

Seismic analysis and design of tunnels within fault ground: A review

open access: yesDeep Underground Science and Engineering, EarlyView.
The research methods of seismic response of tunnels within fault ground, including field investigations, analytical solutions, physical experiments, and numerical simulations, and seismic countermeasures are discussed. The present study examines the shortcomings and limitations of the current research and design, and puts forward proposals for future ...
Xingda Wang   +6 more
wiley   +1 more source

Electrolyte Design Strategies for High‐Energy‐Density Li/Na/K‐Metal Batteries Toward Grid‐Scale Energy Storage: From Liquid to Solid

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This review summarizes key parameters including cathode loading and electrolyte consumption, clarifies the practical application scope of alkali metal batteries, and research progress on advanced electrolytes for grid‐scale energy storage systems. The growing demand for grid‐scale battery energy storage systems (BESSs) has prompted researchers to turn ...
Hui Shao, Zhiwei Ni, Jinkui Feng
wiley   +1 more source

Failure Characteristic and Stability Control of Gob‐Side Entry Retention With Narrow Roadside Filling Wall

open access: yesEnergy Science &Engineering, EarlyView.
A novel collaborative control technology of gob‐side entry retention with narrow roadside filling wall is proposed, wherein anchoring end of anchor cable must penetrate the boundary line of stress peak (plastic zone). ABSTRACT Gob‐side entry retention represents a major technological innovation in the history of coal mining, offering numerous ...
Wenxu Liang, Wei Fu, Ziwen Liu
wiley   +1 more source

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