Results 121 to 130 of about 955,383 (303)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Not everything that can be counted counts, and not everything that counts can be counted.

open access: yes, 2014
The main purpose of the research was to investigate whether the Primary Education Development Plan (PEDP I and II) had achieved the objective of providing quality education in Tanzania. In order to do this the study aimed to uncover the different stakeholders in the implementation process and their roles and contributions towards success or failure ...
openaire   +2 more sources

Counting in the Wild

open access: yes, 2016
In this paper we explore the scenario of learning to count multiple instances of objects from images that have been dot-annotated through crowdsourcing. Specifically, we work with a large and challenging image dataset of penguins in the wild, for which tens of thousands of volunteer annotators have placed dots on instances of penguins in tens of ...
Carlos Arteta   +2 more
openaire   +2 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Manual counting vs. machine counting results.

open access: yes, 2019
Manual counting vs. machine counting results.
Jennifer M. Petitte (6623021)   +4 more
core   +1 more source

To count or not to count? [PDF]

open access: yesSocial Identities, 2015
Pal Ahluwalia, Toby Miller
openaire   +1 more source

Counts count

open access: yes, 2007
Based on the 2006 edition of the Model Size Metrics work- shop, we believe that counts are undervalued as useful model metrics. In this position paper, we provide arguments from the literature so as to consider counts as important metrics for the model measurement.
Monperrus, Martin   +2 more
openaire   +1 more source

A Fish Target Identification and Counting Method Based on DIDSON Sonar and YOLOv5 Model

open access: yesFishes
In order to more accurately and quickly identify and count underwater fish targets, and to address the issues of excessive reliance on manual processes and low processing efficiency in the identification and counting of fish targets using sonar data, a ...
Wei Shen   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

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