Results 81 to 90 of about 731,305 (291)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Highly-efficient state-selective sub-microsecond photoionization detection of single atoms

, 2010
We experimentally demonstrate a detection scheme suitable for state analysis of single optically trapped atoms in less than 1 {\mu}s with an overall detection efficiency {\eta} exceeding 98%.
Henkel, Florian, Hofmann, Julian, Krug, Michael, Rosenfeld, Wenjamin, Weber, Markus, Weinfurter, Harald   +5 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

TasselNetv2: in-field counting of wheat spikes with context-augmented local regression networks

Plant Methods, 2019
Background Grain yield of wheat is greatly associated with the population of wheat spikes, i.e., $$spike~number~\text {m}^{-2}$$ spikenumberm-2 . To obtain this index in a reliable and efficient way, it is necessary to count wheat spikes accurately and ...
Haipeng Xiong, Zhiguo Cao, Hao Lu, Simon Madec, Liang Liu, Chunhua Shen   +5 more
doaj   +1 more source

counting efficiency

, 2014
Citation: 'counting efficiency' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C01377 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Comparison of the efficacy of biodegradable and non-biodegradable scintillation liquids on the counting of tritium- and [14C]-labeled compounds

Brazilian Journal of Medical and Biological Research, 2003
The widespread use of ³H and 14C in research has generated a large volume of waste mixed with scintillation liquid, requiring an effective control and appropriate storage of liquid radioactive waste.
Medeiros R.B., Godinho R.O., Mattos M.F.S.S.   +2 more
doaj  

Efficient and precise cell counting for RNAi screening of Orientia tsutsugamushi infection using deep learning techniques

Intelligent Systems with Applications
Acquiring fluorescent scrub typhus images obtained through RNA interference screening for the analysis of 60 different human genes and 18 control genes poses challenges due to nonuniform or clumped cells and variations in image quality, rendering image ...
Potjanee Kanchanapiboon, Chuenchat Songsaksuppachok, Porncheera Chusorn, Panrasee Ritthipravat   +3 more
doaj   +1 more source

Efficient Algorithms for Counting Gapped Palindromes.

, 2021
A gapped palindrome is a string uvu^{R}, where u^{R} represents the reverse of string u. In this paper we show three efficient algorithms for counting the occurrences of gapped palindromes in a given string S of length N. First, we present a solution in O(N) time for counting all gapped palindromes without additional constraints.
Popa, Andrei, Popa, Alexandru
openaire   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source