Results 91 to 100 of about 494,508 (266)
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Determining the exact number of primes at large magnitudes is computationally intensive, making approximation methods (e.g., the logarithmic integral, prime number theorem, Riemann zeta function, Chebyshev’s estimates, etc.) particularly valuable.
Timothy Ganesan
doaj +1 more source
Construction and counting or generalized Boolean functions
The main result of this paper establishes the number of generalized Boolean functions defined on a finite Boolean algebra.
openaire +3 more sources
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
ON THE COUNTING FUNCTION OF SEMIPRIMES
A semiprime is a natural number which can be written as the product of two primes. The asymptotic behaviour of the function π2(x), the number of semiprimes less than or equal to x, is studied. Using a combinatorial argument, asymptotic series of π2(x) is determined, with all the terms explicitly given.
RAJU BARADI +4 more
openaire +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Lightweight Rebar End Detection Algorithm Based on Improved YOLOv8
Purposes Rebar plays an indispensable role in construction engineering; however, challenges such as densely packed end faces, non-uniform diameter scales, adhesive boundaries, background fusion, and occlusions between end faces have made precise counting
NI Futao +4 more
doaj +1 more source
On the growth of the counting function of Stanley sequences
Given a finite set of nonnegative integers A with no 3-term arithmetic progressions, the Stanley sequence generated by A, denoted S(A), is the infinite set created by beginning with A and then greedily including strictly larger integers which do not introduce a 3-term arithmetic progressions in S(A). Erdos et al.
openaire +2 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

