Results 111 to 120 of about 4,048,224 (281)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

A Biomagnetic Couple Stress Fluid Flow in an Anisotropic Porous Channel with Stretching Walls

East European Journal of Physics
The present study investigates the dynamics of a biomagnetic couple stress fluid within an anisotropic porous channel where the channel walls are stretchable.
R. Vijaya Sree, V. K. Narla, K. Suresh Babu   +2 more
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Comparative Analysis of the Plane Couette Flow of Couple Stress Fluid Under the Influence of Magnetohydrodynamics

East European Journal of Physics
The present study aims to perform a comparative analysis of the plane Couette flow of a couple stress fluid under the influence of magnetohydrodynamics (MHD) using two different methods: the Optimal Auxiliary Function Method (OAFM) and the Homotopy ...
Muhammad Farooq, Ibrar Khan, Rashid Nawaz, Gamal M. Ismail, Huzaifa Umar, Hijaz Ahmad   +5 more
doaj   +1 more source

Influence of couple stress lubricants on hole-entry hybrid journal bearings [PDF]

Jurnal Tribologi, 2017
The analysis of symmetric and asymmetric hole-entry hybrid journal bearings under couple stress lubrication is presented in the present investigation. Equation of Reynolds theorem has been modified for the couple stress lubricant’s flow in the journal ...
Nathi Ram
doaj  

Mixed convection flow of couple stress fluid between vertical parallel plates with radiation and chemical reaction effects [PDF]

, 2014
Paper presented to the 10th International Conference on Heat Transfer, Fluid Mechanics and Thermodynamics, Florida, 14-16 July 2014.This paper studies the effects of thermal radiation and chemical reaction on two dimensional incompressible couple stress ...
Srinivasacharya, D., Kaladhar, K.
core   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Traveling wave solutions for (3 + 1) dimensional equations arising in fluid mechanics

Nonlinear Engineering, 2014
In this note, traveling wave solutions for (3 + 1) dimensional fluid models of incompressible flow are considered. The governing partial differential equations of two models are reduced to ordinary differential equation by employing wave ...
Khan Najeeb Alam, Khan Hassam
doaj   +1 more source