Results 151 to 160 of about 616,847 (259)

Polymyalgia rheumatica in a married couple

, 2012
Christoph Alexander Rüst,1 Beat Knechtle,1,2 Thomas Rosemann,1 Felix Wermelinger31Institute of General Practice and Health Services Research, University of Zurich, Zurich, Switzerland; 2St Gallen Health Center, St Gallen, Switzerland ...
Knechtle B, Wermelinger F, Rüst CA, Rosemann T   +3 more
core  

Beyond the Individual: Couple-Centered Health and Wellness Coaching to Address the Burden of Chronic Conditions. [PDF]

Prev Chronic Dis
Niazi F, Akhtarullah S.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The Evolution of Couple and Family Therapy in Europe: complex but not diverse enough

, 2013
In Europe, family therapy has achieved an extraordinary level of development through the creation of schools, centers, journals and in particular in the European Family Therapy Association.
D'Amore, Salvatore
core  

Effects of Cognitive Behavioral Couple Therapy With Integrated Mindfulness on Mindful Attention, Depressive Symptoms, and Dyadic Adjustment in Low-Income Couples: A Pilot Randomized Clinical Trial. [PDF]

J Marital Fam Ther
Durães RSS, Vargas ZEP, Dias ACG, Lotufo-Neto F, Ramos RT, Serafim AP.   +5 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Economic Costs and Benefits of the Digital OurRelationship Program for Distressed Couples. [PDF]

Fam Process
Doss BD, Guttman S, Metser-Waldman M, Ajmera N, Dopp A.   +4 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

From Compassion to Satisfaction: The Role of Body Appreciation in the Relation Between Flows of Compassion and Couple Satisfaction in Postpartum Women. [PDF]

Healthcare (Basel)
Di Gesto C, Matera C, Nerini A, Rollero C, Caso D, Donizzetti AR, Grano C.   +6 more
europepmc   +1 more source