Results 171 to 180 of about 524,795 (317)

Peristaltic transport of magnetized multi-metallic hybrid nanofluid flow with thermal radiation for heat transfer enhancement. [PDF]

Discov Nano
Tanveer A, Iram, Shflot AS, Abutuqayqah H.   +3 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

'My Bed or Our Bed?': Gendered Negotiations in the Sleep of Same-Sex Couples [PDF]

Sexuality as well as gender can be added to the range of socio-structural factors that influence the social patterning of sleep. This paper draws on in-depth interviews with 20 women and men aged between 45 – 65 years in same-sex couple relationships to ...
Allison Kirkman
core  

Parenting Stress and Couple Relationship Quality Among Transgender and Nonbinary Parents: The Roles of Discrepancy in Division of Childcare Labor and Gender Identity. [PDF]

Fam Process
Fang S, Tornello SL, Spadaro E.
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Neither single, nor in a couple. A study of living apart together in France [PDF]

Among living arrangements, living apart together relationships arouse curiosity on the part of sociologists, demographers and even the media. From a scientific point of view, how have noncohabiting relationships evolved in recent decades?
Arnaud Regnier-Loilier, Eva Beaujouan, Catherine Villeneuve-Gokalp   +2 more
core  

Understanding the Associations Between Attachment Insecurity, Emotional Flooding, and Conflict Behaviors in Prenatal Couples. [PDF]

J Marital Fam Ther
Morgan SD, Woodin EM.
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Parental Education as a Tool for Sustainable Development: The Role of Self-Efficacy and Relationship Satisfaction in Family Well-Being. [PDF]

Behav Sci (Basel)
Roxana Mariana C, Sabin C.
europepmc   +1 more source