Results 141 to 150 of about 3,030,091 (301)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Flow of Two Immiscible Couple Stress Fluids between Two Permeable Beds

open access: yesJournal of Applied Fluid Mechanics, 2016
The paper deals with the flow of two immiscible couple stress fluids between two homogeneous permeable beds. The flow is considered in two zones: zone I and II contain free flow of two immiscible couple stress fluids between two permeable porous beds ...
Dr. Srinivas Jangili   +1 more
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Ferrofluid Based Squeeze Film Lubrication between Rough Stepped Plates with Couple Stress Effect

open access: yesJournal of Applied Fluid Mechanics, 2018
This investigation purposes to study the magnetic fluid based squeeze film behavior on transversely rough stepped plates with the influence of couple stress.
Y. D. Vashi, R. M. Patel, G. M. Deheri
doaj  

Migration of two rigid spheres translating within an infinite couple stress fluid under the impact of magnetic field

open access: yesOpen Physics
In this study, we examine the movement of two hard spheres aligned in a straight line within an incompressible couple stress fluid under the impact of the magnetic field.
El-Sapa Shreen, Alotaibi Munirah Aali
doaj   +1 more source

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