Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
A Size-Dependent Finite Element Method for the 3D Free Vibration Analysis of Functionally Graded Graphene Platelets-Reinforced Composite Cylindrical Microshells Based on the Consistent Couple Stress Theory. [PDF]
Materials (Basel), 2023 Wu CP, Tan TF, Hsu HT.
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Open PhysicsIn this study, we examine the movement of two hard spheres aligned in a straight line within an incompressible couple stress fluid under the impact of the magnetic field.
El-Sapa Shreen, Alotaibi Munirah Aali
doaj +1 more source
Impact of partial slip and lateral walls on peristaltic transport of a couple stress fluid in a rectangular duct. [PDF]
Sci Prog, 2021 Akram S, Saleem N, Umair MY, Munawar S.
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Effectiveness of stress inoculation training on reducing couple burnout in married women
مجله دانشگاه علوم پزشکی گرگان, 2019 Background and Objective: Couple burnout is phenomenon which affects many couples. It is the main cause of emotional divorce, and it can provide a ground for formal divorce of couples.
Fatemeh Rabiee +2 more
doaj
Analysis of newly developed fractal-fractional derivative with power law kernel for MHD couple stress fluid in channel embedded in a porous medium. [PDF]
Sci Rep, 2021 Arif M +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source