Results 71 to 80 of about 805,646 (287)

On the notions of energy tensors in tetrad-affine gravity

open access: yes, 2017
We are concerned with the precise modalities by which mathematical constructions related to energy-tensors can be adapted to a tetrad-affine setting. We show that, for fairly general gauge field theories formulated in that setting, two notions of energy ...
Canarutto, Daniel
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Balancing torques in membrane-mediated interactions: Exact results and numerical illustrations

open access: yes, 2007
Torques on interfaces can be described by a divergence-free tensor which is fully encoded in the geometry. This tensor consists of two terms, one originating in the couple of the stress, the other capturing an intrinsic contribution due to curvature.
B. Antonny   +15 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Thermodynamics Analysis of Radiative Hydromagnetic Couple Stress Fluid through a Channel [PDF]

open access: yes, 2017
This work applies second law of thermodynamics to analyse the effect of radiation on electrically conducting couple stress fluid through a channel. A constant magnetic field is introduced across the flow channel and the resulting Navier- Stokes and ...
Gbadeyan, J.A.   +2 more
core   +1 more source

Comments on 2D dilaton gravity system with a hyperbolic dilaton potential

open access: yes, 2017
We proceed to study a (1+1)-dimensional dilaton gravity system with a hyperbolic dilaton potential. Introducing a couple of new variables leads to two copies of Liouville equations with two constraint conditions.
Kyono, Hideki   +2 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Surface roughness effect on thermohydrodynamic analysis of journal bearings lubricated with couple stress fluids

open access: yesNonlinear Engineering, 2019
The paper presents, surface roughness effect for thermo-hydrodynamic analysis of journal bearings extended to couple stress lubricants with high polymer additives. A modified energy equation is simultaneously solved with heat transfer equation as well as
Awati Vishwanath B., Kengangutti Ashwini
doaj   +1 more source

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