Results 71 to 80 of about 3,030,091 (301)
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Strain gradient theory with couple stress for crystalline solids
A new phenomenological strain gradient theory for crystalline solid is proposed. It fits within the framework of general couple stress theory and involves a single material length scale Ics. In the present theory three rotational degrees of freedom omega
Chen, SH (reprint author), Chinese Acad Sci, Inst Mech, LNM, Beijing 100080, Peoples R China. +2 more
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Double-Diffusive Convection of Synovial (Couple-Stress) Fluid in the Presence of Hall Current Through a Porous Medium [PDF]
An investigation made on the effect of Hall currents on double-diffusive convection of a compressible synovial (couple-stress) fluid in the presence of a horizontal magnetic field through a porous layer is considered.
Singh, M., M. Singh
core +1 more source
Impact of permeability and fluid parameters in couple stress media on rotating eccentric spheres
This study elucidates the axisymmetric rotation of two eccentric spheres immersed in an incompressible couple stress fluid within a porous annular region.
Al-Hanaya Amal, El-Sapa Shreen
doaj +1 more source
The Character of Couples and Couple Stresses in Continuum Mechanics
In this paper, the concepts of moments and couples in mechanics are examined from a fundamental perspective. Representing a couple by its moment vector is very useful in rigid body mechanics, where the states of internal stresses and deformation are not studied.
openaire +2 more sources
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Effectiveness of interpersonal communication on couple is message delivery process that are capable to achieve suitable understanding and comprehension between husband and wife, which content of information is delivered appropriately, and takes places in
FARISA NURDIANI, Ika Febrian Kristiana
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

