Results 101 to 110 of about 2,685,840 (293)

A Comparative Study of the Effectiveness of Emotionally Focused Couple Therapy and Gottman Couple Therapy on Improving Self-Soothing, Marital Trust, Emotional Intimacy, and Emotional Bank Account [PDF]

مجله علوم روانشناختی
Background: Marital relationships constitute one of the most important contexts for emotion regulation, the development of trust, and the experience of emotional intimacy, and disturbances in these domains play a fundamental role in couples’ conflicts ...
Atefe khalili, Isaac Rahimian-Boogar, Mehdi Ghodrati Mirkouhi, Siavash Talepasand   +3 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Comparison of the effectiveness of couple therapy based on acceptance and commitment (ACT), and gottman’s couple therapy on marital intimacy among conflicting couples

مجله علوم روانشناختی, 2022
Background: Marital intimacy refers to the interaction between couples that leads to feelings of closeness, love and attention, and research has shown that it is a importanat factor in creating marital satisfaction. Despite the publication of the results
seyedrahman hosseini, Azizallah Tajikesmaeili, bagher Sanaei zaker, Mohsen Rasuli   +3 more
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Comparison of the effectiveness of couple therapy based on acceptance and commitment and couple therapy based on guttman method on marital commitment

مجله علوم روانشناختی, 2022
Background: The severance of emotional bond between couples is the consequence of infidelity by one of them, which imposes a lot of psychological pressure and by creating negative emotions may lead to mutual infidelity or lack of marital commitment in ...
Zohreh Halajian, Vahideh Babakhani, Jafar Pooyamanesh, Alireza Jafari   +3 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The impact of cancer on the relationship of the couple [PDF]

, 2008
Includes bibliographical references (leaves 77-81).Includes abstract.This study aimed to investigate the impact that the diagnosis of cancer has on the relationship of couples where one of the partners have been diagnosed with cancer. In order to achieve
Hitchcock, Sandra M
core   +1 more source

Effectiveness of Self-Regulation Couple Therapy intervention on marital satisfaction and partner abuse (Non-physical)

Mediterranean Journal of Clinical Psychology, 2016
the aim of this research was to investigate effectiveness self-regulation couple therapy intervention on marital and partner abuse. in a semi-experimental with experimental and control group design, 24 couples were selected by convenient sampling method ...
Rasoul Heshmati, Ali Khaleghkhah, Esa Jafari, Maryam Marandi   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Comparative Study of the Effectiveness of Emotional-Focused Couple Therapy and Narrative Couple Therapy on Marital Conflicts

Taḥqīqāt-i ̒Ulūm-i Raftārī, 2019
Aim and Background: Disturbance of marital relationship is one of the most common stressors in recent decade which has a significant negative impact on the satisfaction of couples and their children.
Alireza Torkan, Hadi Farhadi, Mohsen Golparvar   +2 more
doaj