Results 111 to 120 of about 2,685,840 (293)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The effectiveness of localized couple therapy based on reality therapy on marital burnout of conflicting couples

open access: yesTaḥqīqāt-i ̒Ulūm-i Raftārī, 2022
Aim and Background: Today, one of the achievements of the family institution and one of the factors threatening the foundation and center of the family is the conflicts that occur in the relationship between couples.
Fatemeh Khazaei   +3 more
doaj  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Journal of Proton Therapy: Call for Papers

open access: yes, 2015
Journal of Proton Therapy (JPT) is an international open access, peer-reviewed journal, which publishes original research, technical reports, reviews, case reports, editorials, and other materials on proton therapy with focus on radiation oncology ...
Proton Therapy, Journal of
core  

Snow Therapy : guérir le couple ou se guérir du couple ?

open access: yes, 2021
International audience« Snow Therapy : guérir le couple ou se guérir du couple ? », in Nicolas Balutet et André-Alain Morello, Corps, Genre, Santé, Toulon : Effigi, p.
Martin, Tiphaine
core   +1 more source

COUN 860 Marriage & Couple Therapy

open access: yes, 1991
Course syllabus for COUN 860 Marriage & Couple Therapy Course description: Approaches to counseling which focus on couple interactions rather than individual pathology are presented.
Matteson, David R.
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Discourse Analysis of Constructions of Couple Therapy [PDF]

open access: yes, 2015
Under-utilization, premature termination, and lack of between-session engagement have been discussed in the couple therapy literature in terms of how they negatively impact the course and outcome of couple therapy. The goal of the present research was to
Sommerlund, Merete
core  

The Effectiveness of Self Regulation Couple Therapy on Marital Satisfaction, Identity Style and Family Problem Solving

open access: yesروانشناسی بالینی و شخصیت, 2016
Introduction: The purpose of this study was to investigate the effectiveness of self regulation couple therapy on marital satisfaction, identity style and family problem solving.
Nasibe Mansouri   +3 more
doaj  

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