Results 131 to 140 of about 2,685,840 (293)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Mediation techniques in Couple and Family Therapy: two clinical vignettes
, 2012 Through the presentation of two clinical vignettes – one from a couple therapy and another one from a family therapy- therapeutic efficacy of utilizing graphic tasks, like graphic-projective instruments (Anzieu, Chabert, 1997), or free children’s ...
Greco, Ondina
core
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Psychoanalytic Couple Therapy: Consultation and Therapeutic Framework
Al-Jamie Journal in Psychological Studies and Educational SciencesIn this scientific paper, the two researchers discussed a therapeutic process derived from psychoanalytic theory, represented by analytical couples therapy, which serves couples in the first place and the marital relationship in the second, in relation ...
Lounes LALLEM, Rachid BELKHEIR
doaj
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Infants in couple and family therapy
, 2016 This authoritative reference assembles prominent international experts from psychology, social work, and counseling to summarize the current state of couple and family therapy knowledge in a clear A-Z format.
Salivar, Emily Georgia +2 more
core +1 more source
Armaghane Danesh Bimonthly Journal, 2017 Background & aim: Couple burnout is one of the phenomena which involve many couples, it is among the main causes of emotional divorce, and without proper management and treatment, and it can lay the ground for formal divorce among couples.
M Mohammadi +5 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
مجله علوم روانشناختی, 2018 Background: In the literature of couples ' relationships, how couples deal with is dependent on how to assess the individual and the impact of the individual and their shared life as well as the attachment styles of each couple.
Fariba Ebrahimi Tazekand +2 more
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