Results 121 to 130 of about 5,402,366 (275)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Particle-hole mixed Bogoliubov quasiparticles and Cooper instability in single-unit-cell FeSe/SrTiO3 films

Communications Materials
In conventional superconductors, Bogoliubov quasiparticles and Cooper instability provide a paradigm to describe the superconducting state and the superconducting transition, respectively.
Zhiyuan Wei, Shaozhi Li, Bo Liu, Xiupeng Sun, Yinqi Hu, Shuai Sun, Shuting Peng, Yang Luo, Linwei Huai, Jianchang Shen, Bingqian Wang, Yu Miao, Zhipeng Ou, Yao Wang, Kun Jiang, Junfeng He   +15 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

First-order electroweak phase transition at finite density

Journal of High Energy Physics
We study the Electroweak phase transition with the Standard Model effective field theory at finite temperature and finite density. Utilizing the dimensional reduction approach, we construct the tree dimensional thermal effective field theory at finite ...
Renhui Qin, Ligong Bian
doaj   +1 more source

Study on electromagnetic response in cavity to relic high-frequency gravitational waves with nontensorial polarizations

Nuclear Physics B
The relic gravitational waves (RGWs) originating from the early stages of the universe represent one of the most significant and highly focused targets for future gravitational wave (GW) detections, due to that these waves contain crucial information ...
Minghui Zhang, Hao Wen
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Properties of the $$\eta _q$$ η q leading-twist distribution amplitude and its effects to the $$B/D^+ \rightarrow \eta ^{(\prime )}\ell ^+ \nu _\ell $$ B / D + → η ( ′ ) ℓ + ν ℓ decays

European Physical Journal C: Particles and Fields
The $$\eta ^{(\prime )}$$ η ( ′ ) -mesons in the quark-flavor basis are mixtures of two mesonic states $$|\eta _{q}\rangle =|{\bar{u}} u+{\bar{d}} d\rangle /\sqrt{2}$$ | η q ⟩ = | u ¯ u + d ¯ d ⟩ / 2 and $$|\eta _{s}\rangle =|{\bar{s}} s\rangle .$$ | η s
Dan-Dan Hu, Xing-Gang Wu, Hai-Bing Fu, Tao Zhong, Zai-Hui Wu, Long Zeng   +5 more
doaj   +1 more source