Results 121 to 130 of about 4,061,968 (313)
Parameterized post-Newtonian analysis of quadratic gravity and solar system constraints
This work systematically investigates the post-Newtonian behavior of general quadratic gravity in the weak-field regime. By extending the Einstein–Hilbert action to include quadratic curvature terms as $$\mathcal {L}\propto R-\lambda C^2+\mu R^2$$ L ∝ R -
Jie Zhu, Hao Li
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The $$\eta ^{(\prime )}$$ η ( ′ ) -mesons in the quark-flavor basis are mixtures of two mesonic states $$|\eta _{q}\rangle =|{\bar{u}} u+{\bar{d}} d\rangle /\sqrt{2}$$ | η q ⟩ = | u ¯ u + d ¯ d ⟩ / 2 and $$|\eta _{s}\rangle =|{\bar{s}} s\rangle .$$ | η s
Dan-Dan Hu +5 more
doaj +1 more source
ANN-Based Inverse Modeling and Global Sensitivity Analysis of a CAR1 Damper
Friction dampers are widely used as passive energy dissipation devices in seismic protection systems; however, their response depends on numerous interacting parameters, complicating design.
Magdalini Titirla, Walid Larbi
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Radiative cooling effects on black hole hot accretion flows around the sub-Bondi radius
Aims. It is difficult to implement numerical simulations on a region extending from the vicinity of a black hole to the Bondi radius. Most previous numerical simulations have primarily concentrated on the region close to the black hole.
Liu Mu-Qing, Yang Xiao-Hong, Bu De-Fu
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

