Results 231 to 240 of about 5,400,307 (274)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Coupled pharmacokinetic model unveils drug-drug interactions in plasma concentration. [PDF]

PLoS One
Huang H, Li C, Chen Q, Zhuang C, Yu L, Jin W, Li X.   +6 more
europepmc   +1 more source

Thermal management of lithium-ion batteries: from single cooling to hybrid cooling. [PDF]

RSC Adv
Qianqian Z, Wei Z, Siyang W, Xufei Y, Guanglin L, Dongliang S, Bo Y.   +6 more
europepmc   +1 more source

Coupled oscillator mechanism extends the amplifying effect of outer hair cells to high frequencies. [PDF]

Sci Rep
Iwasa KH.
europepmc   +1 more source

High-spin state dynamics and quintet-mediated emission in intramolecular singlet fission. [PDF]

Nat Commun
Grüne J, Montanaro S, Bradbury TW, Sharma A, Dowland S, Gillett AJ, Gorgon S, Millington O, Myers WK, Behrends J, Clark J, Rao A, Bronstein H, Greenham NC.   +13 more
europepmc   +1 more source

Advanced preclinical testing of a design-optimized ceramic bearing for a cervical total disc replacement. [PDF]

PLoS One
Kölle L, Pryce G, Beadling AR, Bryant M, Hall RM, Ferguson SJ, Helgason B.   +6 more
europepmc   +1 more source

Designing strongly coupled polaritonic structures via statistical machine learning. [PDF]

Proc Natl Acad Sci U S A
Yang Y, Guo X, Zhang S, Dai Q, Deng K, Liu JS.   +5 more
europepmc   +1 more source