Results 91 to 100 of about 11,512,847 (280)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A Common Coupled Fixed Point Theorem in Complex Valued Metric Space
The aim of this paper is to establish a unique common coupled fixed point theorem for two mappings satisfying a rational inequality in complex valued metric space.
Nawneet Hooda, Savitri Savitri
openaire +1 more source
Common fixed point theorems for fuzzy mappings [PDF]
summary:In this paper, we prove common fixed point theorems for fuzzy mappings satisfying a new inequality initiated by Constantin [6] in complete metric ...
Rashwan, R. A., Ahmed, Magdy A.
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Some coupled coincidence and common fixed point results for a hybrid pair of mappings in 0-complete partial metric spaces [PDF]
In this paper we extend some coupled coincidence and common fixed point theorems for a hybrid pair of mappings obtained by Abbas et al. (Fixed Point Theory Appl.
Shukla, Satish +3 more
core +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The purpose of this paper is to present some existence and uniqueness results for common fixed point theorems for θ-ϕ contraction mappings with two metrics endowed with a directed graph.
P. Charoensawan, W. Atiponrat
doaj +1 more source

