Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Research on boost conversion of SiC-based laser power supply for aerospace applications. [PDF]
Zhang X, Wang Y, Shi B, Liu Y.
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Environment-Dependent Downlink Pinching-Antenna Systems: Spectral-Energy Efficiency Tradeoffs and Design. [PDF]
Zha X, Chen Y, Wang Q.
europepmc +1 more source
Coupled fixed point theorems in C*-algebra-valued b-metric spaces [PDF]
Stojan Radenović +3 more
openalex +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Sensitivity analysis enlightens effects of connectivity in a Neural Mass Model under Control-Target mode. [PDF]
Vallet A +8 more
europepmc +1 more source
An interesting approach to the existence of coupled fixed point
Pulak Konar +3 more
openalex +1 more source
Fixed Point Theorems for Geraghty Type Contractive Mappings and Coupled Fixed Point Results in 0-Complete Ordered Partial Metric Spaces [PDF]
Esra Yolaçan
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