Results 221 to 230 of about 682,008 (293)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Crosstalk Effects in a Dual ToF-Based Tactile-Proximity Sensing Platform Integrated in a Flat PMMA Light Guide. [PDF]
Ogurcovs A +4 more
europepmc +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Microvibration Testing and Decoupling for Space Payloads with Large Inertia, High Stiffness, and Discrete Interfaces. [PDF]
Jiang R +7 more
europepmc +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
On the Mode Localization Between Two Unidentical Resonators with Different Bending Modes for Acceleration Sensing. [PDF]
Yang B, Lyu M, Zhao J, Kacem N.
europepmc +1 more source
TripleWin: Fixed-Point Equilibrium Pricing for Data-Model Coupled Markets [PDF]
Hongrun Ren +5 more
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Stabilising spatiotemporal dynamics of mussel-algae coupled map lattices model via proportional-differential control. [PDF]
Zhu Y +4 more
europepmc +1 more source

