Results 71 to 80 of about 7,223,590 (284)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

A coupled random fixed point result with application in Polish spaces

Sahand Communications in Mathematical Analysis, 2017
Summary: In this paper, we present a new concept of random contraction and prove a coupled random fixed point theorem under this condition which generalizes stochastic Banach contraction principle. Finally, we apply our contraction to obtain a solution of random nonlinear integral equations and we present a numerical example.
Rashwan, Rashwan Ahmed, Hammad, Hasanen Abuel-Magd   +1 more
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Infrared Fixed Points and Fixed Lines for Couplings in the Chiral Lagrangian

, 2000
9 pages, 2 encapsulated postscript figures, uses epsfig.sty; 2 more postscript figures ...
Atance, Mario, Schrempp, Barbara
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Coupled Fixed Point Theory in Subordinate Semimetric Spaces

Symmetry
The aim of this paper is to study the coupled fixed point of a class of mixed monotone operators in the setting of a subordinate semimetric space. Using the symmetry between the subordinate semimetric space and a JS-space, we generalize the results of Senapati and Dey on JS-spaces.
Areej Alharbi, Maha Noorwali, Hamed H. Alsulami   +2 more
openaire   +2 more sources

An interesting approach to the existence of coupled fixed point

AIMS Mathematics, 2020
<abstract> <p>Configure a coupled fixed point result on a nonempty set engaging a partial order and induced with a quasi-metric in the sense of Kunzi ^{[<xref ref-type="bibr" rid="b12">12</xref>]} in the framework of $\mathcal{G}$-metric spaces.
Pulak Konar, Sumit Chandok, Samir Kumar Bhandari, Manuel De la Sen   +3 more
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source