Results 91 to 100 of about 638,866 (302)

A particle-resolved heat-particle-fluid coupling model by DEM-IMB-LBM

Journal of Rock Mechanics and Geotechnical Engineering
Multifield coupling is frequently encountered and also an active area of research in geotechnical engineering. In this work, a particle-resolved direct numerical simulation (PR-DNS) technique is extended to simulate particle-fluid interaction problems ...
Ming Xia, Jinlong Fu, Y.T. Feng, Fengqiang Gong, Jin Yu   +4 more
doaj   +1 more source

A numerical study of bubble growing during saturated and sub-cooled flow boiling in micro channels [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014)
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Formulation of a method for predicting coupled convective and radiative heat transfer about a blunt body [PDF]

Method for predicting coupled convective and radiative heat transfer about blunt ...
Engel, C. D., Spradley, L. W.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Numerical analysis of the influence of the design type of the channel of heat network on its thermal conditions and heat loss

Известия высших учебных заведений: Проблемы энергетики, 2017
The results of the numerical analysis of thermal regimes and heat loss of the two-channel underground heating networks with using the convective-conductive model of heat transfer are presented. The two-dimensional coupled stationary problem of convective-
V. Y. Polovnikov
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Analysis of coupled heat and moisture transfer in masonry structures

, 2008
Evaluation of effective or macroscopic coefficients of thermal conductivity under coupled heat and moisture transfer is presented. The paper first gives a detailed summary on the solution of a simple steady state heat conduction problem with an emphasis ...
B Tomková, C Boutin, H Künzel, I Oezdemir, J Auriault, J Grunewald, J Novák, J Philip, J Zeman, Jan Sýkora, Jan Vorel, Jiří Šejnoha, M Biot, M Hassanizadech, M Hassanizadech, M Kaminski, Michal Šejnoha, R De Boer, R Schirmer, R Černý, RW Lewis, Tomáš Krejčí   +21 more
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Hygrothermal behavior of energy diaphragm wall and the induced heat and moisture interaction with adjacent underground space

Underground Space
In the field of design and application of the energy diaphragm wall (EDW), plenty of research was focused on thermal performances and induced mechanical behaviors.
Xu Zhou, Xiaoling Cao, Ziyu Leng, Chao Zeng, Yanping Yuan, Shady Attia   +5 more
doaj   +1 more source