Results 141 to 150 of about 1,148,154 (395)

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Flow and heat transfer of an exponential stretching sheet in a viscoelastic liquid with Navier slip boundary condition

Journal of Applied Fluid Mechanics, 2015
Viscoelastic boundary layer flow and heat transfer over an exponential stretching continuous sheet have been investigated in this paper. Numerical solution of the highly non-linear momentum equation and heat transfer equation are obtained.
A. S. Chethan, Sekhar G. N, P.G. Siddheshwar   +2 more
doaj  

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

A particle-resolved heat-particle-fluid coupling model by DEM-IMB-LBM

Journal of Rock Mechanics and Geotechnical Engineering
Multifield coupling is frequently encountered and also an active area of research in geotechnical engineering. In this work, a particle-resolved direct numerical simulation (PR-DNS) technique is extended to simulate particle-fluid interaction problems ...
Ming Xia, Jinlong Fu, Y.T. Feng, Fengqiang Gong, Jin Yu   +4 more
doaj  

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

A device for rapid determination of thermophysical properties of phase-change wind-tunnel models [PDF]

An experimental method for direct measurement of the thermophysical properties of wind tunnel heat transfer models was developed. The technique consists of placing the model under a bank of high intensity, radiant heaters so that the fast opening water ...
Creel, T. R., Jr.
core   +1 more source

A Simulation Model for Coupled Heat Transfer and Moisture Transport under the Action of Heat Source in Unsaturated Soils. [PDF]

Sci Rep, 2018
Jin H, Guo Y, Deng H, Qi X, Gui J.
europepmc   +1 more source

Coupled Heat and Mass Transfer in a Laminar Flow around a Flat Plate with a Uniform Heat Flux

, 1974
Yasuo Kurosaki
openalex   +2 more sources

Spheroid Cell Aggregation Enhanced by Enzyme‐Free Ultrasound‐Detached Cells

Advanced Biology, EarlyView.
This study demonstrates that ultrasound‐based, enzyme‐free cell detachment accelerates spheroid formation by preserving surface proteins, reducing variability, and enhancing cell aggregation. Comparable engraftment and improved spatial organization in co‐cultured spheroids are observed.
Julien van Delft, Chikahiro Imashiro, Yuta Kurashina, Makoto Hirano, Jun Homma, Shinsuke Mochizuki, Hideharu Shimozawa, Kenjiro Takemura   +7 more
wiley   +1 more source