Results 61 to 70 of about 258,460 (270)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

The Metacoupling Framework Informs Stream Salmonid Management and Governance

Frontiers in Environmental Science, 2020
Stream salmonid fisheries are ecologically and socioeconomically important at local to global scales throughout the world. Although these fisheries are interacting systems of biota, habitats, and humans, systematic social-ecological integration across ...
Andrew K. Carlson, Andrew K. Carlson, William W. Taylor, Sara M. Hughes   +3 more
doaj   +1 more source

Coupled human and natural systems: A multi-agent-based approach

Environmental Modelling & Software, 2007
A major force affecting many forest ecosystems is the encroachment of residential, commercial and industrial development. Analysis of the complex interactions between development decisions and ecosystems, and how the environmental consequences of these decisions influence human values and subsequent decisions will lead to a better understanding of the ...
Michael Monticino, Miguel F. Acevedo, Baird Callicott, Travis Cogdill, Christopher Lindquist   +4 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Synthesis of human-nature feedbacks

Ecology and Society, 2015
In today’s globalized world, humans and nature are inextricably linked. The coupled human and natural systems (CHANS) framework provides a lens with which to understand such complex interactions.
Vanessa Hull, Mao-Ning Tuanmu, Jianguo Liu   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

How urban impervious surface shapes bird foraging behavior in an arid city [PDF]

PeerJ
Wildlife behavior and interactions in urban ecosystems can vary across landscape types and species, with some birds dominating human-derived resources.
Simone Vega Rabelo, Jeffrey D. Haight, Heather L. Bateman   +2 more
doaj   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Who let the dog out? Dog owner attitudes and economics regulate the potential negative impact of domestic dogs on wildlife in a reserve network

Conservation Science and Practice
Many domestic animals have a profound impact on endangered species through complex interactions and spillover effects in and between coupled human and natural systems.
Yue Weng, William Joseph McShea, Hongbo Yang, Zhuojin Zhang, Weiming Lin, Fang Wang   +5 more
doaj   +1 more source