Results 31 to 40 of about 4,076 (264)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A Coupled-Inductor Interleaved LLC Resonant Converter for Wide Operation Range

open access: yesEnergies, 2022
In this paper, a coupled-inductor interleaved LLC resonant converter (CI-ILLC) was proposed, which can achieve extensive operation range applications by multiplexing inductors and switches.
Qianfan Zhou   +3 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Using a coupled inductor controlled by fuzzy logic to improve the efficiency of a Buck converter in a PV system

open access: yesE3S Web of Conferences, 2017
Photovoltaic generators (PVG) produce a variable power according to the solar radiation (G) and temperature (T). This variation affects the sizing of the components of DC / DC converters, powered by such PVG, and make it difficult. The effects may differ
Abouchabana Nabil   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Dimensioning and Modeling of a Circular Inductor Integrated in a Boost Converter [PDF]

open access: yesЖурнал нано- та електронної фізики, 2016
This paper presents the dimensioning and modeling of a circular inductor integrated in a Boost micro converter. At first, we define the characteristics of the Boost micro converter, which is the starting point for the design our component, taking into ...
Y. Benhadda, A. Hamid, T. Lebey
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Hybrid Switched Capacitor Three Winding Coupled Inductor High Step-Up DC-DC Converter

open access: yesIEEE Access
Switched capacitor cells have been studied in recent years. These approaches allow different new topologies to be generated. One such technique is the hybrid converter, where a coupled inductor and switched capacitor can be combined. Thus, in this paper,
Antonio Manuel Santos Spencer Andrade   +2 more
doaj   +1 more source

High Efficiency and Voltage Conversion Ratio Bidirectional Isolated DC-DC Converter for Energy Storage System

open access: yesIEEE Access, 2022
This paper proposes a high efficiency and conversion ratio bidirectional isolated DC-DC converter with three-winding coupled inductor, which can fulfil storage system charging and discharging. The proposed topology is improved from traditional Buck-Boost
Yu-En Wu, Bo-Hau Pan
doaj   +1 more source

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