Results 101 to 110 of about 2,146,599 (300)
Fix-lines and stability domain in the vicinity of the coupled third order resonance
, 2015 The single particle stability in a circular accelerator is of concern especially for operational regimes involving beam storage of hours. In the proximity to a resonance this stability domain shrinks, and the phase space fragments into a jungle of exotic
Franchetti, Giuliano, Schmidt, Frank
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
cAMP Accumulation Assays Using the AlphaScreen® Kit (PerkinElmer)
Bio-Protocol, 2013 Cyclic adenosine monophosphate (cAMP) is an intracellular signaling messenger derived from the catalytic conversion of ATP, and is a major product of activated Gs protein-coupled receptors. Conversely, formation of cAMP is inhibited by Gi protein-coupled
Cassandra Koole +2 more
doaj +1 more source
A SNAP coupled microresonator delay line
Optics Express, 2013 A delay line fabricated of a chain of SNAP (Surface Nanoscale Axial Photonics) coupled microresonators is demonstrated. In contrast to resonant delay lines demonstrated to date, the slow light in this structure is enhanced by the 2R (Rotation + Reflection) effect realized due to the 3D propagation of light along the surface of a SNAP fiber.
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Journal of Marine Science and Engineering, 2019 The paper discusses the effects of mooring configurations on the dynamic response of a submerged floating offshore wind turbine (SFOWT) for intermediate water depths.
Yane Li +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
EPJ Applied Metamaterials, 2014 This paper presents a new class of magnetically scanned leaky wave antennas (LWAs), incorporating ferrite (or possibly magnetoelectric composite), for wide angle beamsteering.
Apaydin Nil +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Scientific World Journal, 2014 We intend to design a broadband band-pass filter with notch-band, which uses coupled transmission lines in the structure, using new models of coupled transmission lines.
Navid Daryasafar +3 more
doaj +1 more source