Results 41 to 50 of about 654,900 (196)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Cross‐talk reduction in metamaterial and non‐uniform transmission lines
IET Microwaves, Antennas & PropagationThe electromagnetic compatibility analysis of RF circuitry is essential due to the adverse effects on sensitive components. Two metamaterial unit cells with slow‐wave properties are presented for cross‐talk reduction in transmission lines. The analytical
Hamid Reza Abbasi +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
IET Microwaves, Antennas & PropagationTraditional quarter‐wavelength parallel‐line couplers (QWPLC) in microstrip form suffer heavily in low directivity because of unbalanced even‐mode and odd‐mode phase velocities.
Yun Liu, Xiaojie Zhang, Zhuo Li
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Energies, 2019 Protection of mutually coupled transmission lines poses special challenges to protection engineers, since the general principles outlining the expected performance of the protection elements are based on simplified versions of the issues affecting them ...
José de Jesús Jaramillo Serna +1 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
A compact ultra wideband bandpass filter using arrow coupled lines with defected ground structure
Journal of Electrical Systems and Information Technology, 2014 A new ultra wideband bandpass filter (UWB-BPF) using arrow coupled lines and U-slot defected ground structures (U-DGS) is proposed. The input and output feeding lines are connected to the coupled lines placed on the conductor side of the substrate while ...
Deena A. Salem +2 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A Compact Transmission-Line Self-Matched Negative Group Delay Microwave Circuit
IEEE Access, 2017 A compact self-matched negative group delay (NGD) circuit without the need for an external matching circuit is proposed. The proposed NGD circuit is composed of two-port open-circuited coupled lines, a short-circuited transmission line and two resistors ...
Te Shao +4 more
doaj +1 more source