Results 111 to 120 of about 19,589,973 (304)

Semiclassical solutions for linearly coupled Schrodinger equations

Electronic Journal of Differential Equations, 2014
We consider the system of coupled nonlinear Schrodinger equations $$\displaylines{ -\varepsilon^2\Delta u+a(x) u=H_{u}(x, u, v)+\mu(x) v, \quad x\in \mathbb{R}^N,\cr -\varepsilon^2\Delta v+b(x) v=H_{v}(x, u, v)+\mu(x) u, \quad x\in \mathbb{R}^N,\cr
Sitong Chen, Xianhua Tang
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Numerical Scheme for Solution of Coupled System of Initial Value Fractional Order Fredholm Integro-Differential Equations with Smooth Solutions

Journal of Mathematical Extension, 2015
We study shifted Legendre polynomials and develop some operational matrices of integrations. We use these operational matrices and develop new sophisticated technique for numerical solutions to the following coupled system of fredholm integro ...
H. Khalil, R. A. Khan
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Multivariable Coupled System Control Method Based on Deep Reinforcement Learning. [PDF]

Sensors (Basel), 2023
Xu J, Li H, Zhang Q.
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Design and Vibration Suppression Performance of a Coupled Isolation System for Marine Rotary Pump Units

Applied Sciences
To address the need for high-efficiency vibration isolation in marine rotary pump units, this paper proposes a coupled isolation system that integrates vibration isolators and flexible connectors, and systematically investigates its vibration suppression
Feng Chen, Yinglong Zhao, Zhen Zhang
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Analysis of a Coupled System of Implicit Fractional Differential Equations of Order α ∈ (1, 2] with Anti-Periodic Boundary Conditions

Fractal and Fractional
This paper investigates a coupled system of nonlinear implicit fractional differential equations of order α∈(1,2] subject to anti-periodic boundary conditions.
Areen Al-Khateeb, Muath Awadalla, Murugesan Manigandan, Salma Trabelsi   +3 more
doaj   +1 more source