Results 151 to 160 of about 19,589,973 (304)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

The Rise of the Digital Health Technology-AI Coupled System in the AI Era of Drug Development. [PDF]

J Clin Pharmacol
Zhang H, Innes GK, Santiago J, Suliman A, Xiao N, Zhu H, Paraoan D, Siegel J, Gong Y, Huang R, Wang M, Zhang L, Liu Q.   +12 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Extracting wave solutions of coupled system of dual-mode variant boussinesq equation via two analytical methods. [PDF]

Sci Rep
Arshed S, Akram G, Sadaf M, Ahmed M, Birhanu A, Abd El-Rahman M.   +5 more
europepmc   +1 more source

Projecting an ultra-strongly-coupled system in a non-energy-eigenbasis with a driven nonlinear resonator. [PDF]

Sci Rep, 2020
Endo S, Matsuzaki Y, Kakuyanagi K, Saito S, Lambert N, Nori F.   +5 more
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Energy-Efficient Seawater Lithium Extraction via a Reversible Redox-Hydrogen Coupled System. [PDF]

Nat Commun
Wang Y, Yang S, Liu Y, Wang C, Pan H, Zhang Z, He P, Zhou H.   +7 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Proof of Heteroclinic Orbit in One-Dimensional Arrays of Discretely-Coupled Cells

, 2007
A one-dimensional array of discretely-coupled cells is considered. The cell consists of a capacitor and a nonlinear 3-segment piecewise linear resistor. The proof of the existence of a heteroclinic orbit in the associative continuous system will be given.
Domine M.W. Leenaerts, Discretely-coupled Cells   +1 more
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