Results 71 to 80 of about 2,260,510 (314)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
BuildingsThe construction of reinforced concrete (RC) structures inevitably consumes an excessive number of rebars, leading to significant cutting waste and carbon emissions.
Daniel Darma Widjaja +2 more
doaj +1 more source
A 77-GHz Six-Port Sensor for Accurate Near-Field Displacement and Doppler Measurements
Sensors, 2018 A continuous-wave (CW) radar sensor design based on a millimetre-wave six-port interferometer is proposed. A complete sensor prototype is conceived of, fabricated and measured at 77 GHz for short-range professional and industrial applications.
Homa Arab +4 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Optics Express, 2013 We demonstrate a novel on-chip two-mode division multiplexing circuit using a tapered directional coupler-based TE(0)&TE(1) mode multiplexer and demultiplexer on the silicon-on-insulator platform.
Yunhong Ding +5 more
semanticscholar +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
All-fiber fused directional coupler for highly efficient spatial mode conversion.
Optics Express, 2014 We model and demonstrate a simple mode selective all-fiber coupler capable of exciting specific higher order modes in two- and few-mode fibres with high efficiency and purity. The coupler is based on inter-modally phase-matching the propagation constants
R. Ismaeel +4 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Microstrip Hybrid Coupler with a Wide Stop-Band Using Symmetric Structure for Wireless Applications
Journal of Microwaves, Optoelectronics and Electromagnetic ApplicationsIn this paper, a wide stop-band microstrip coupler is presented. The proposed structure consists of coupled lines and step impedance cells, which are integrated to operate at 2.82 GHz for wireless applications.
A. Rezaei, L. Noori
doaj +1 more source