Results 151 to 160 of about 359,082 (309)
To Couple or not to Couple? Exploring Vibronic Coupling in Organic Semiconductors
The Earth is heating up—an observation grounded not in speculation but in extensive scientific evidence, as illustrated in Figure 1. The accelerating rise in global temperature is not only a planetary signal but also a scientific and technological call to action.
openaire +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Power couples in antiquity: an initial survey
, 2019 This chapter offers a first survey of the phenomenon of the “power couple” in Greco-Roman antiquity. After presenting the main biases of the literary and documentary sources which limit our knowledge about ancient power couples, the chapter summarizes ...
Bielman Sánchez, Anne
core +1 more source
Integrative Sex and Couples Therapy A Therapist's Guide to New and Innovative Approaches
Featuring new approaches combining sex therapy and relationship counseling, Integrative Sex & Couples Therapy brings treatment skills into practice, with real-world experiences, interventions, techniques, strategies, and case examples.Cover -- Copyright -
Nelson, Tammy.
core
'My Bed or Our Bed?': Gendered Negotiations in the Sleep of Same-Sex Couples [PDF]
Sexuality as well as gender can be added to the range of socio-structural factors that influence the social patterning of sleep. This paper draws on in-depth interviews with 20 women and men aged between 45 – 65 years in same-sex couple relationships to ...
Allison Kirkman
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Portraying Mixed-Agenda Couples: Insights From Large-Scale Data Sets. [PDF]
J Marital Fam TherTang Y +4 more
europepmc +1 more source
The UT Conversation Library (UTCL) is a collection of appr. 200 hours of real-life conversations in various settings, many of the telephone conversations, collected by the late Robert Hopper, professor in the Department of Communication Studies, and his ...
Hopper, Robert, 1945-1998
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source