Results 171 to 180 of about 167,956 (269)

Individual and spousal weight trajectories and their associations with health-related quality of life: a longitudinal population-based cohort from the Tehran Lipid and Glucose Study (2001-2018). [PDF]

BMJ Open
Naseri P, Amiri P, Cheraghi L, Zareie Shab Khaneh A, Azizi F.   +4 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The Feasibility, Acceptability, and Preliminary Effects of a Prenatal Preventive Intervention Program for Coparenting: A Pilot Study in Japan. [PDF]

Healthcare (Basel)
Masui Y, Yamazaki A.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Spousal Discrepancies in Perceived Needs of People Living with Alzheimer's Disease: A Mixed-Methods Study of Caregivers' Perspective Taking and Dyadic Communication. [PDF]

J Appl Gerontol
Huo M, Tran RT, Meyer OL, Lyons KS, Mroz EL.   +4 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Beyond carrier frequency: a preliminary multicenter study of simultaneous couple-based comprehensive carrier screening for common and rare genetic disorders. [PDF]

Genome Med
Xiao B, Liu H, Sun Y, Su X, Chinese Medical Doctor Association of Genetics Counselling Board, Xie X, Xu Z, Ren F, Peng Y, Hui L, Xu L, Zhang C, Duan J, Zhang J, Li J, Xue S, Liao S, Liu L, Zhao Z, Yuan D, Qiu J, Zhang F, Huang Y, Ha Y, Yu L, Tang K, Li X, Pan W, Shu J, Zhu J, Meng L, Xu C, Mao A, Yan N, Yu Y.   +34 more
europepmc   +1 more source

The Elderly Couple [PDF]

The Permanente Journal, 2019
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Loneliness within couples coping with cancer: prevalence, associations with physical and mental health, and potential benefits of dyadic exercise. [PDF]

Front Aging
Winters-Stone K, Stoyles SA, Dieckmann N, Sokolova AO, Graff JN, Hung A, Wang S, Lyons KS.   +7 more
europepmc   +1 more source