Results 121 to 130 of about 2,561,669 (294)
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Heterosexual couples, gender discourse, and the production of relational subjectivity [PDF]
This study is situated in feminist and poststructural theory. The focus of the study is heterosexual relationships. In particular, the study investigates the shaping effects of patriarchal discourses on the relational subjectivity of a woman partner; how
Morris, Brian
core
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Conversation therapy for agrammatism: exploring the therapeutic process of engagement and learning by a person with aphasia. [PDF]
A recent systematic review of conversation training for communication partners of people with aphasia has shown that it is effective, and improves participation in conversation for people with chronic aphasia.
Best, W +5 more
core
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Behavioral couples therapy versus cognitive behavioral therapy for problem gambling: a randomized controlled trial. [PDF]
Nilsson A +4 more
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
For whose sake do couples relocate? Gender, career opportunities and couples’ internal migration in Sweden [PDF]
The aim with this study is to examine how career possibilities in the man’s and the woman’s occupations – in the country as a whole, as well as in the region where the couple resides – affect heterosexual couples’ regional mobility. The context is Sweden
Ström, Sara, Brandén, Maria
core
Relationship violence among couples seeking therapy: common couple violence or battering?
Relationship violence is highly prevalent among couples seeking therapy (Ehrensaft and Vivian, 1996; Jouriles and O'Leary, 1985), yet few couple therapists regularly assess for violence (Dimidjian, Berns, and Jacobson, 1999), and there is limited ...
Simpson, Lorelei E +3 more
core +1 more source
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source

