Results 71 to 80 of about 2,561,669 (294)

Working With Parts Of the Self Within the EFT Framework

open access: yesПсихология и Психотерапия Семьи
Emotionally Focused Therapy (EFT) and the Internal Family Systems (IFS) model are independent and theoretically complete approaches. The former works with the dyad through the lens of attachment theory, while the latter focuses on the internal system of ...
Oksana Trushina
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The effectiveness of training based on group narrative therapy on the couples intimacy

open access: yesمجله علوم روانشناختی, 2017
The studies have shown that social psychologists have used narrative methods to test the hypothesis of the dynamics of close, intimate and kindly relationships between couples in order to improve family functions and promote intimacy.
Maryam Moslemi, Hakimeh Aghaei
doaj  

Couples therapy: effectiveness of treatment and long-term follow-up

open access: yes, 2006
Most couples therapy theories are developed and tested in the USA. In this clinical study, we investigated such therapies in a Swedish context. Over 300 couples were enrolled in the study of whom just under half completed the end-of-treatment assessment ...
Lundblad, AM   +2 more
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Comparison of the effectiveness of couple therapy methods in the theory of Choice, acceptance and commitment (ACT), and integrative couple therapy in marital commitment of couples

open access: yesمجله علوم روانشناختی, 2019
Background: Marital commitment and its various dimensions are among the most important factors in the sustainability of a shared life. Much research has been done using paired therapeutic approaches of theory of choice, acceptance, and commitment, and ...
Maryam Sedghi   +3 more
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The effectiveness of compassion-focused couple therapy on positive and negative emotional expressiveness and intimacy expressiveness in incompatible couples [PDF]

open access: yesمجله علوم روانشناختی
Background: A decrease in positive emotional expressiveness, a decrease in intimacy expressiveness, and an increase in negative emotional expressiveness are related to marital incompatibility.
Ali Derikvandi, Maryam Esfahaniasl
doaj  

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