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The high-speed-train pantograph is a complex structure that consists of different rod-shaped and rectangular surfaces. Flow phenomena around the pantograph are complicated and can cause a large proportion of aerodynamic noise, which is one of the main ...
Yongfang Yao +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The widespread deployment of the Internet of Things (IoT) is promoting interest in simultaneous wireless information and power transfer (SWIPT), the performance of which can be further improved by employing a reconfigurable intelligent surface (RIS).
X Zhang (6084905) +4 more
core +4 more sources
<p>4 functions are available to comput coupling soil moisture-temperature coupling based on <a href="https://agupubs.onlinelibrary.wiley.com/doi/10.1029/2012GL053703">Miralles et al.
Marc Lemus-Canovas
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Analysis of the Transonic Buffet Characteristics of Stationary and Pitching OAT15A Airfoil
Transonic buffet flow is a classical complex and unstable flow that has a negative effect on aircraft fly safety. Therefore, it is crucial to study the unsteady characteristics of buffet flow. The numerical analysis method is very useful in achieving the
Xueyuan Nie +5 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Data-Driven Adaptive Control of Transonic Buffet via Localized Morphing Skin
Transonic shock buffet, characterized by large-amplitude self-sustained shock oscillations arising from shock wave/boundary layer interactions, poses significant challenges to aircraft handling quality and structural integrity.
Yuchen Zhang +5 more
doaj +1 more source
Surrogate Based Optimization of Aerodynamic Noise for Streamlined Shape of High Speed Trains
Aerodynamic noise increases with the sixth power of the running speed. As the speed increases, aerodynamic noise becomes predominant and begins to be the main noise source at a certain high speed.
Zhenxu Sun, Ye Zhang, Guowei Yang
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

