Results 81 to 90 of about 23,458,446 (299)

Research on the coordinated relationship between human activities and ecosystem service value in the Arid Region, Northwestern China

Frontiers in Ecology and Evolution
IntroductionArid and semi-arid regions encompass nearly 40% of the Earth’s land surface and are characterized by extensive undeveloped land, scarce water resources, and fragile ecosystems.
Shiyao Liu, Zhijian Gao, Wanghai Tao, Quanjiu Wang, Lijun Su, Yan Sun, Yuyang Shan, Zhi Qu   +7 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Coupling between flexible ship and liquid sloshing using potential flow analysis and their effect on wave induced loads

, 2010
The purpose of this study is to investigate the influence of hull flexibility on the hydrodynamic forces and moments associated with liquid sloshing, as well as the dynamic characteristics = (e.g. resonance frequencies) of the whole system.
Tan, M., Lee, Y., Miao, S.H., Temarel, P.   +3 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Coupling isogeometric analysis with deep learning for stability evaluation of rectangular tunnels

, 2023
The problem considered in this paper is for the stability evaluation of a rectangular tunnel in undrained clay during lining process. The approach adopted involved the use of isogeometric analysis (IGA) and the upper bound limit analysis formulation for ...
Nguyen-Minh, Toan, Nguyen, Tan, Shiau, Jim, Toan Nguyen-Minh, Bui-Ngoc, Tram, Tan Nguyen, Trung Nguyen-Thoi, Nguyen-Thoi, Trung, Tram Bui-Ngoc, Jim Shiau   +9 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Analysis of Slope Stability of Small and Medium Earth-rock Dams underSeepage-stress Coupling and Fluctuation of Reservoir Level

Renmin Zhujiang, 2020
In order to study the influence mechanism and law of seepage-stress coupling and thefluctuation of reservoir level on slope stability of small and medium homogeneous earth-rock dams,according to the principle of unsaturated seepage and the simplified ...
SU Zhengyang, ZHANG Zhitao, LI Hanzhang
doaj  

freeze-thaw cycle, seasonal frozen soil, geogrid, reinforced characteristic

Yantu gongcheng xuebao, 2019
The soils are a transfer medium between supporting force of excavation face and earth pressure of soil chamber, and their performance directly affect the control of earth pressure of soil chamber, the supporting force of excavation faces, and the ...
XIAO Chao 1,2,3, TAN Li-xin 2,3, CHEN Ren-peng 1, ZHONG Zhi-quan 2,3, YANG Jun-sheng 4
doaj   +1 more source

Coupling Analysis and Control of a Turboprop Engine

Proceedings of the 12th International Conference on Informatics in Control, Automation and Robotics, 2015
The goal of this paper is to describe the different steps of the decentralized control design applied on a turboprop engine. An important part of the present approach is the interaction analysis, which leads to the choice of a decentralized strategy with a full compensator.
Le Brun, Christophe, Godoy, Emmanuel, Beauvois, Dominique, Liacu, Bogdancristian, Noguera, Ricardo   +4 more
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source