Results 121 to 130 of about 5,328,774 (332)
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
The Influence of Torsion on Transmission Function Asymetric Twin Core Fibre
The transmission function of twin core fibre is determined by his fibre length and coupling length if only one of its cores is excited. For design of attenuation components or sensors it is useful known transmission dependence twin core fibres on ...
Daniel Kacik, Ivan Turek, Ivan Martincek
doaj
Tilt-to-length (TTL) coupling noise arises from angular misalignments of interfering beams in optical path length (OPL) measurements and significantly impacts the accuracy of interferometry measurement systems.
Jia Shen +9 more
doaj +1 more source
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
High power, broadband, coaxial to microstrip bi‐directional coupler in the VHF/UHF band
Broadband couplers consist usually of multiple coupled lines that are each a quarter wave‐length long. Herein, in contrast to conventional methods, a short length of a microstrip line is coupled to a coaxial line.
Tohid Naeimi, Arash Ahmadi
doaj +1 more source
Lengthscale effects on exchange coupling in Co-Pt L10 + L12 nanochessboards
The Co-Pt nanochessboard is a quasi-periodic, nanocomposite tiling of L10 and L12 magnetic phases that offers a novel structure for the investigation of exchange coupling, relevant to permanent magnet applications. Periodicity of the tiling is controlled
Eric P. Vetter +6 more
doaj +1 more source
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source

