Results 121 to 130 of about 6,557,444 (383)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Preparation and mechanism research on hydrophobic coupling modification of HTV silicone rubber

open access: yesFrontiers in Materials
Neat high-temperature vulcanized silicone rubber (HTV SR) showed bad hydrophobicity due to the existence of a large number of inorganic reinforcing fillers on its surface, which affected its security application in outdoor insulation systems.
Qiang Li   +5 more
doaj   +1 more source

Cyclization-Carbonylation-Cyclization Coupling Reaction of Propargyl Ureas with Palladium(II)-Bisoxazoline Catalyst

open access: yesMolecules, 2012
The cyclization-carbonylation-cyclization coupling reaction (CCC-coupling reaction) of propargyl ureas catalyzed by Pd<sup>II</sup>(box) complexes afforded symmetrical ketones bearing two 2-amino-2-oxazoline groups in good to moderate yields.
Hiroyuki Takayama   +6 more
doaj   +1 more source

THERMODYNAMIC ANALYSIS OF SYNTHESIS GAS AND HIGHER HYDROCARBONS PRODUCTION FROM METHANE [PDF]

open access: yes, 2012
This chapter focused on thermodynamic chemical equilibrium analysis using method of direct minimization of Gibbs free energy for all possible methane reactions with oxygen (partial oxidation of methane), carbon dioxide (CO2 reforming of methane), steam ...
Istadi, Istadi
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Quantum Langevin Equations and Stability

open access: yes, 1998
Different quantum Langevin equations obtained by coupling a particle to a field are examined. Instabilities or violations of causality affect the motion of a point charge linearly coupled to the electromagnetic field.
Jaekel, Marc-Thierry, Reynaud, Serge
core  

Iron/Copper Co-Catalyzed C-C Cross-Coupling Reaction [PDF]

open access: yes, 2011
Development of carbon-carbon bond forming reactions forms the crux of modern synthetic organic chemistry. Of various methods developed for facilitating C-C bond formation, cross coupling reactions has been well explored. Initial attempt was made by using
Mohapatra, Swapna Sarita
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Dinuclear PhosphoiminoBINOL-Pd Container for Malononitrile: Catalytic Asymmetric Double Mannich Reaction for Chiral 1,3-Diamine Synthesis

open access: yesScientific Reports, 2018
A phosphoiminoBINOL ligand was designed to form a dinuclear metal complex that could hold a malononitrile molecule. The dinuclear bis(phosphoimino)binaphthoxy-Pd2(OAc)2 complex catalyzed a double Mannich reaction of N-Boc-imines with malononitrile to ...
Takayoshi Arai   +4 more
doaj   +1 more source

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