Results 121 to 130 of about 132,623 (304)

Cubic and higher-order supergravity couplings for AdS vacua using Exceptional Field Theory

Journal of High Energy Physics
We show how to use Exceptional Field Theory to efficiently compute n-point couplings of all Kaluza-Klein modes for vacua that can be uplifted from maximal gauged supergravities to 10/11 dimensions via a consistent truncation.
Bastien Duboeuf, Emanuel Malek, Henning Samtleben   +2 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Measurements of W ± Z production cross sections in pp collisions at vs=8?TeV with the ATLAS detector and limits on anomalous gauge boson self-couplings

, 2016
This paper presents measurements of W ± Z production in pp collisions at a center-of-mass energy of 8 TeV. The gauge bosons are reconstructed using their leptonic decay modes into electrons and muons.
Carlos Chavez Barajas (16190231), Itzebelt Santoyo Castillo (16219298), Kerim Suruliz (8315862), Lily Asquith (4465900), Fabrizio Salvatore (4461772), Mark Sutton (4463308), Alessandro Cerri (4464562), Tina Potter (16061984), Antonella De Santo (4462306), Benedict Allbrooke (4466344), Iacopo Vivarelli (4464559), et al The ATLAS Collaboration (16232882)   +11 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Adaptive Output Synchronization of Coupled Fractional-Order Memristive Reaction-Diffusion Neural Networks

Fractal and Fractional
This article discusses the adaptive output synchronization problem of coupled fractional-order memristive reaction-diffusion neural networks (CFOMRDNNs) with multiple output couplings or multiple output derivative couplings.
Feng You, Hong-An Tang, Yanhong Wang, Zi-Yi Xia, Jin-Wei Li   +4 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Correlated C-C and C-O bond conformations in saccharide hydroxymethyl groups: Parameterization and application of redundant 1H-1H, 13C-1H and 13C-13C NMR J-couplings

Methyl α- and β-pyranosides of d-glucose and d-galactose 1−4 were prepared containing single sites of 13C-enrichment at C4, C5, and C6 (12 compounds), and 1H and 13C{1H} NMR spectra were obtained to determine a complete set of J-couplings (1J, 2J, and 3J)
B. Hertz (20134290), Q. Wu (2889887), I. Carmichael (2645569), A. S. Serianni (20115126), R. Stenutz (20134287), C. Thibaudeau (3035877), T. Klepach (20132547), S. Zhao (1466308)   +7 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source