Results 161 to 170 of about 4,021,853 (297)

Strengthening bioinformatics education: e-learning initiatives across ELIXIR Nodes and Communities. [PDF]

F1000Res
Zahn-Zabala M, Ahokas M, Batut B, Beier S, Botzki A, Cardona A, Gruden K, Korpelainen E, Lehtivaara M, Leskosek B, Mirăuță B, Mishra A, Pommier C, Poterlowicz K, Rasche H, Sand O, Waterhouse R, Wittke S, Zenoaga-Barbăroșie C, Anton M, Wibberg D.   +20 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Exploring the Impact of Open Pedagogy on Minority Students' Motivation, Computational Thinking, and Perceived Learning in Interactive Computer Game Development. [PDF]

J Intell
Kuo YT, Kuo YC.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Primary Literature as the Course Design Centerpiece in a General Chemistry Course That Prepares Undergraduates for Research. [PDF]

ACS Omega
Knoerzer TA, Gardner KA, Reimann MD, Hicks BW.   +3 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Leveraging learning management systems in medical education: a scoping review of use, outcomes, and improvement pathways. [PDF]

Med Educ Online
Kamath SG, Nayak KR, Nayak V, Verma S.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The importance of Dentistry in cases of domestic violence and neglect against the elderly.

Journal of Oral Research, 2017
José LSA Rodríguez, Luiz R. Paranhos, Sigmar de Mello Rode   +2 more
doaj   +1 more source

Design and practice of Oral Biomaterials course for education of stomatology in Chinese universities. [PDF]

BMC Oral Health
You R, Liu L, Han F, Liao M, Yan B, Jiang H, Chen C, Xie H.   +7 more
europepmc   +1 more source