Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
An Ai-Supported Biostatistics E-Course Based on the Successive Approximation Model: Evaluation in Medical Education. [PDF]
Omarbekova N +5 more
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Resource Use in Introductory Biology: Evaluating Latent Patterns, Demographic Covariates, and Effects on Final Course Grade. [PDF]
Weatherton M, Aikens M.
europepmc +1 more source
Teaching an advanced processing course with hands-on projects
The present work discusses an advanced processing course with 10 magisterial courses (2h each) where theoretical aspects are covered and three hands-on projects.
International Conference on Materials Education +1 more
core
Reference material for courses
Reference material for reference course and winter/summer schools for CSP ...
openaire +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Workplace Chinese training in a Chinese-managed factory in Morocco: a transfer-sensitive CIPP evaluation. [PDF]
Zhang Y, Huang Z, Gao Q.
europepmc +1 more source
Reading course materials in e-book form and on mobile devices
In 2001-3 The Open University launched a project on e-book production and deployment, funded by a university initiative in e-learning. The project set out to investigate technical aspects of producing Open University course books and other course ...
Kukulska-Hulme, Agnes
core

