Results 71 to 80 of about 1,349,206 (301)

Final Report Factors Influencing Stability of Granular Base Course Mixes

open access: yes, 1991
To evaluate the various factors influencing the stability of granular base course mixes, three primary goals were included in the project: (1) determination of a suitable and realistic laboratory method of compaction; (2) effect of gradation, density

core  

Measuring the strength of brittle materials by depth-of-penetration testing [PDF]

open access: yes, 2010
Based on an energy conservation model, the strength offered by a number of brittle materials has been calculated from depth-of-penetration (DOP) test results. Each material was completely penetrated by a tungsten carbide cored projectile of known kinetic
Hazell, Paul J., P J Hazell
core   +1 more source

Application of Team-Working Model to Training OER Writers of Distance and E-learning Pathways Course Materials in Ghanaian Public Universities

open access: yesWest African Journal of Open and Flexible Learning
Collaborative course design and materials development has been a project that depended on qualified subject matter specialists and educationists working together to produce distance learning materials.
A.A. Saah
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Learning to Learn Online: Course Materials

open access: yes, 2021
This document shared the contents of the massive open online course (MOOC) on Learning to Learn Online, developed by the Faculty of Humanities and Social Sciences, Athabasca University, Canada.
Cleveland-Innes, Martha   +2 more
core  

RDM Course Materials

open access: yes
The Knowledge Force (KF) "Course Materials" group of the Knowledge Hub aims to enhance collaboration and reduce duplication of efforts in the field of research data management (RDM) training across Flanders. Recognizing the lack of exchange between institutions in this domain, our initiative seeks to provide research support staff with a centralized ...
Vlietinck, Hanne, Sterckx, Kim
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Development of Course Modules for Materials Experiments

open access: yes, 1995
Recent U.S. government-sponsored studies of the decline of international competitiveness have reported that one of the most severe problems is the lack of education of future engineers in synthesis and processing of advanced engineered materials.
Vedula, K., Constant, Kristen
core  

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