Results 81 to 90 of about 16,893,129 (340)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Transformation for an open education repository: issues associated with IT and computing distance learning course materials

open access: yes, 2007
The number of Open Educational Resource Repositories available worldwide continues to grow and many contain course materials from campus-based institutions.
Wilson, Tina
core  

Code of Best Practices in Fair Use for OpenCourseWare [PDF]

open access: yes, 2009
Provides a code of best practices to help those preparing OpenCourseWare -- course materials in digital form available for free online -- to interpret and apply fair use under U.S. copyright law.

core  

07 Intern Assignment Biological Adaptations [PDF]

open access: yes, 2020
WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core   +1 more source

Assessment of challenges in developing self-instructional course materials at the National Open University of Nigeria

open access: yes, 2012
The National Open University of Nigeria (NOUN) is Nigeria’s only university dedicated to providing education through the use of distance instructional methods.
C. A. Okonkwo
semanticscholar   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Open Knowledge Resources for Higher Education: Scholarly Publications, Course Materials, Academic Software [PDF]

open access: yes, 2006
This paper will explain why electronic knowledge resources in academia cannot only be regarded as private commodities, but also as public goods. After sketching a concept of public goods for a postnational, global society, three types of electronic ...
Thomas Pfeffer
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Pre-service Possibilities: Reconsidering \u27\u27Art for the Elementary Educator [PDF]

open access: yes, 2007
Art for the Elementary Educator courses are sites of possibility in the field of art education, particularly art education oriented toward curriculum integration and meaningful art experiences.
Buffington, Melanie L., Kushins, Jodi
core   +1 more source

09 Intern Assignment Refractory Materials [PDF]

open access: yes, 2020
WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core   +1 more source

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