Results 261 to 270 of about 1,131,860 (291)
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Covalent modification and metabolic control analysis
European Journal of Biochemistry, 1990A study of the sensitivity properties of metabolic systems containing covalently modifiable enzymes and cascades has been carried out with the aid of metabolic control analysis. We have considered how the theorems of metabolic control analysis must be modified to take into account covalently modifiable enzymes, and have used these results to ...
J R, Small, D A, Fell
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Inheritance of a covalent histone modification
Science, 2015Epigenetics Genomic DNA is the repository of all genetic information and is packaged into chromatin. Chromatin is also a repository of regulatory information in the form of covalent marks added to the histones that package the DNA. These marks can determine tissue- and organ-specific gene expression patterns, which must be transmitted to daughter cells
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Improvement by Covalent and Noncovalent Modification
1978As mentioned in earlier Chapters, cyclodextrins exhibit many interesting features such as rate effects, stereospecificity, enantiomeric specificity, etc., in organic reactions. However, there is one serious hortcoming of cyclodextrins as catalysts.
Myron L. Bender, Makoto Komiyama
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Covalent modification of aromatase by a radiolabeled irreversible inhibitor
Journal of Steroid Biochemistry, 19857 alpha-Substituted 4-androstene-3,17-diones are effective inhibitors of aromatase. The microsomal enzyme complex has a greater affinity for several of these inhibitors than for the substrate androstenedione, with 7 alpha-(4'amino)phenylthio-4-androstene-3,17-dione being the most potent competitive inhibitor of the series.
C E, Snider, R W, Brueggemeier
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Posttranslational covalent modification of proteins.
Science (New York, N.Y.), 1978A search for derivatized amino acids in proteins has shown that the extent of posttranslational modification of proteins is quite substantial. While only 20 primary amino acids are specified in the genetic code and are involved as monomer building blocks in the assembly of the polypeptide chain, about 140 amino acids and amino acid derivatives have ...
R, Uy, F, Wold
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Covalent modification of nuclear proteins during aging
1975An in vitro assay system has been established to study acetylation and phosphorylation of nuclear proteins from isolated nuclei. Phosphorylation of neclear proteins reached a peak within 5 min while maximum acetylation occurred about 10 min later. The rate of acetylation of liver nuclear proteins in 15 min incubation was significantly higher in "old ...
Liew, C C, Gornall, A G
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