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Digital Surface‐Enhanced Raman Scattering With Event Counting and Spectrum Learning for Label‐Free Protein Quantification

Advanced Intelligent Systems, EarlyView.
A statistical and machine learning‐assisted surface‐enhanced Raman scattering (SERS) framework is developed for label‐free quantification of low‐abundance analytes, including proteins. Combining digital SERS event counting with binomial regression and an artificial neural network (ANN) trained on full spectra, the approach achieves picomolar detection ...
Eni Kume, James Rice
wiley +1 more source

HYPOTHESIS TESTING ON LINEAR STRUCTURES OF HIGH DIMENSIONAL COVARIANCE MATRIX. [PDF]

Ann Stat, 2019
Zheng S, Chen Z, Cui H, Li R.
europepmc +1 more source

Generalized Task‐Driven Design of Soft Robots via Reduced‐Order Finite Element Method‐Based Surrogate Modeling

Advanced Intelligent Systems, EarlyView.
A unified, reusable modeling pipeline enables task‐driven design of soft robots across actuator families and task scenarios. High‐fidelity simulations are compressed into compact pseudo‐rigid‐body joint surrogates, while a design‐conditioned meta‐model generates new surrogates from geometry parameters without rerunning finite element method.
Yao Yao, David Howard, Perla Maiolino
wiley +1 more source

On the Significance of the Quantum Mechanical Covariance Matrix. [PDF]

Entropy (Basel), 2018
Carmi A, Cohen E.
europepmc +1 more source

Speckle Skin‐Based Multimodal Tactile Perception for Fine Robotic Manipulation

Advanced Intelligent Systems, EarlyView.
SpeckleTac, a miniature vision‐based tactile sensor, utilizes a speckle‐pattern skin and optical flow‐based scalable virtual marker tracking. Combined with advanced algorithms, it achieves high‐resolution 3D surface reconstruction, precise contact perception, and stable grasping capabilities.
Jiayuan Zhang +6 more
wiley +1 more source

Xstainer: A Novel Virtual Staining Tool Powered by Advanced Deep Learning Techniques

Advanced Intelligent Systems, EarlyView.
Xstainer is a deep learning–based virtual staining framework that converts hematoxylin and eosin‐stained whole slide images into multiple histochemical stains, including Masson's trichrome, Periodic acid‐Schiff, Jones methenamine silver, and Toluidine blue.
Fatma Nur Kinali +15 more
wiley +1 more source

Uncovering renewable energy policy impact channels on land values, the local farm structure, and farmland heterogeneity

American Journal of Agricultural Economics, EarlyView.
Abstract Germany's Renewable Energy Sources Act (REA), enacted in 2000 and subsequently amended, subsidized national renewable energy production with fixed feed‐in tariffs for renewable energy sources (RE) from wind, solar, and biogas. Empirical studies suggest that the policy was creating windfall effects for landowners and attribute farmland use ...
Lars Isenhardt +6 more
wiley +1 more source

Multitemporal SAR Image Despeckling Based on a Scattering Covariance Matrix of Image Patch. [PDF]

Sensors (Basel), 2019
Ma X, Wu P.
europepmc +1 more source

Efficacy and Safety of Subcutaneous Efgartigimod PH20 in Adults With Primary Immune Thrombocytopenia (ADVANCE SC): A Multicenter, Randomized, Double‐Blinded, Placebo‐Controlled, Phase 3 Trial

American Journal of Hematology, EarlyView.
ABSTRACT Primary autoimmune thrombocytopenia (ITP) is characterized by thrombocytopenia, bleeding, and reduced health‐related quality of life. In the Phase 3 ADVANCE IV study, intravenous efgartigimod induced significant platelet count responses versus placebo in patients with chronic ITP. ADVANCE SC, a Phase 3, multicenter, randomized, double‐blinded,
Nichola Cooper +546 more
wiley +1 more source

Eigenvalues of the covariance matrix as early warning signals for critical transitions in ecological systems. [PDF]

Sci Rep, 2019
Chen S, O'Dea EB, Drake JM, Epureanu BI.
europepmc +1 more source

covariance matrix estimation
covariance estimation