Results 51 to 60 of about 550,309 (325)
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Nonparametric goodness‐of‐fit testing for parametric covariate models in pharmacometric analyses
CPT: Pharmacometrics & Systems Pharmacology, 2021 The characterization of covariate effects on model parameters is a crucial step during pharmacokinetic/pharmacodynamic analyses. Although covariate selection criteria have been studied extensively, the choice of the functional relationship between ...
Niklas Hartung +3 more
doaj +1 more source
Bayesian Analysis of Hazard Regression Models under Order Restrictions on Covariate Effects and Ageing [PDF]
, 2007 We propose Bayesian inference in hazard regression models where the baseline hazard is unknown, covariate effects are possibly age-varying (non-proportional), and there is multiplicative frailty with arbitrary distribution.
Bhattacharjee, Arnab +1 more
core +4 more sources
Robust Tests for Treatment Effect in Survival Analysis under Covariate-Adaptive Randomization
, 2019 Covariate-adaptive randomization is popular in clinical trials with sequentially arrived patients for balancing treatment assignments across prognostic factors which may have influence on the response.
Shao, Jun, Ye, Ting
core +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
A Conditional Randomization Test to Account for Covariate Imbalance in Randomized Experiments
Journal of Causal Inference, 2016 We consider the conditional randomization test as a way to account for covariate imbalance in randomized experiments. The test accounts for covariate imbalance by comparing the observed test statistic to the null distribution of the test statistic ...
Hennessy Jonathan +4 more
doaj +1 more source
Nonparametric analysis of covariance [PDF]
The Annals of Statistics, 2001 In the problem of testing the equality of k regression curves from independent samples we discuss three methods using nonparametric estimation techniques of the regression function. The first test is based on a linear combination of estimators for the integrated variance function in the individual samples and in the combined sample. The second approach
Dette, Holger, Neumeyer, Natalie
openaire +5 more sources
CSF Biomarker‐Based Cognitive Trajectories in Parkinson's Disease‐Subjective Cognitive Decline
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive complaints without objective cognitive impairment in Parkinson's Disease, termed Parkinson's Disease‐Subjective Cognitive Decline (PD‐SCD), have been associated with cognitive decline. However, its progression is heterogeneous, highlighting the need for improved identification of patients at greater risk for deterioration ...
Jon Rodriguez‐Antiguedad +7 more
wiley +1 more source
Frontiers in Psychology, 2015 A number of statistical textbooks recommend using an analysis of covariance (ANCOVA) to control for the effects of extraneous factors that might influence the dependent measure of interest. However, it is not generally recognized that serious problems of
Bruce A Schneider +2 more
doaj +1 more source