Results 51 to 60 of about 540,575 (323)
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Robust Tests for Treatment Effect in Survival Analysis under Covariate-Adaptive Randomization
, 2019 Covariate-adaptive randomization is popular in clinical trials with sequentially arrived patients for balancing treatment assignments across prognostic factors which may have influence on the response.
Shao, Jun, Ye, Ting
core +1 more source
Quasi Score is more efficient than Corrected Score in a polynomial measurement error model [PDF]
, 2005 We consider a polynomial regression model, where the covariate is measured with Gaussian errors. The measurement error variance is supposed to be known. The covariate is normally distributed with known mean and variance.
Kukush, Alexander +2 more
core +2 more sources
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
A Conditional Randomization Test to Account for Covariate Imbalance in Randomized Experiments
Journal of Causal Inference, 2016 We consider the conditional randomization test as a way to account for covariate imbalance in randomized experiments. The test accounts for covariate imbalance by comparing the observed test statistic to the null distribution of the test statistic ...
Hennessy Jonathan +4 more
doaj +1 more source
Rerandomization to improve covariate balance in experiments
, 2012 Randomized experiments are the "gold standard" for estimating causal effects, yet often in practice, chance imbalances exist in covariate distributions between treatment groups.
Morgan, Kari Lock, Rubin, Donald B.
core +1 more source
Covariance in plasticity [PDF]
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2013 Covariance is imposed to the second law of thermodynamics and consequences are shown for elastic-perfectly plastic bodies. In this setting, pointwise balances of standard and configurational actions, constitutive restrictions on the first Piola–Kirchhoff stress and the Eshelby one, and the structure of the dissipation are all derived from a unique ...
openaire +4 more sources
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden +15 more
wiley +1 more source
Frontiers in Psychology, 2015 A number of statistical textbooks recommend using an analysis of covariance (ANCOVA) to control for the effects of extraneous factors that might influence the dependent measure of interest. However, it is not generally recognized that serious problems of
Bruce A Schneider +2 more
doaj +1 more source
Nonparametric goodness‐of‐fit testing for parametric covariate models in pharmacometric analyses
CPT: Pharmacometrics & Systems Pharmacology, 2021 The characterization of covariate effects on model parameters is a crucial step during pharmacokinetic/pharmacodynamic analyses. Although covariate selection criteria have been studied extensively, the choice of the functional relationship between ...
Niklas Hartung +3 more
doaj +1 more source